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dc.creatorBallesteros Sánchez, Antonioes
dc.creatorPeraza Nieves, Jorgees
dc.creatorCasablanca Piñera, Annaes
dc.creatorRodríguez Calvo de Mora, Marinaes
dc.creatorCatalán Coronado, Sarayes
dc.creatorTorras Sanvicens, Josepes
dc.creatorBorroni, Davidees
dc.creatorSánchez González, José Maríaes
dc.creatorRocha de Lossada, Carloses
dc.date.accessioned2024-06-04T08:17:55Z
dc.date.available2024-06-04T08:17:55Z
dc.date.issued2023
dc.identifier.citationBallesteros Sánchez, A., Peraza Nieves, J., Casablanca Piñera, A., Rodríguez Calvo de Mora, M., Catalán Coronado, S., Torras Sanvicens, J.,...,Rocha de Lossada, C. (2023). Scheimpflug Corneal Densitometry Patterns at the Graft–Host Interface in DMEK and DSAEK: A 12-Month Longitudinal Comparative Study. Journal of Clinical Medicine, 12 (22), 7133. https://doi.org/10.3390/jcm12227133.
dc.identifier.issn2077-0383es
dc.identifier.urihttps://hdl.handle.net/11441/159646
dc.description.abstractBackground: To compare corneal densitometry (CD) patterns at the graft–host interface between Descemet Membrane Endothelial Keratoplasty (DMEK) and Descemet Stripping Automated Endothelial Keratoplasty (DSAEK). Corneal densitometry is a quantitative assessment that objectively evaluates corneal clarity and optical quality by measuring the light backscatter from the cornea. Methods: Fifty-one eyes that received DMEK or DSAEK surgery for corneal endothelium dysfunction were evaluated. The primary endpoint included CD patterns at the graft–host interface, which were assessed by the Pentacam HR device at the center point of the corneal horizontal meridian (CDcentral), and at six points on the central circumference of the cornea (with a total diameter of 4 mm) (CDI,II,III,IV,V,VI). Secondary endpoints included the best-corrected distance visual acuity (BCDVA), central corneal thickness (CCT), and graft thickness (GT). All of the evaluations were performed at follow-up appointments one, three, six and twelve months after the procedure. Results: DMEK showed a significant overall CD reduction of -7.9 +- 8.5 grayscale unit (GSU) compared to DSAEK (p < 0.001). In addition, the DMEK group showed significantly lower CDCentral,I,II,III,IV,V,VI values at follow-up appointments one, three, six and twelve months after the procedure compared to the DSAEK group (p < 0.001). BCDVA, CCT and GT were in favor of the DMEK group with a mean value of 0.39 +- 0.35 LogMar, 552.2 +- 71.1 um and 11.03 +- 1.4 um, respectively (p < 0.001). Conclusions: CD patterns at the graft–host interface seem to be different depending on the endothelial keratoplasty procedure. This provides specific insight into CD changes in this critical region of surgery, which may provide a better understanding of the postoperative evolution of these patients.es
dc.formatapplication/pdfes
dc.format.extent11 p.es
dc.language.isoenges
dc.publisherMDPIes
dc.relation.ispartofJournal of Clinical Medicine, 12 (22), 7133.
dc.rightsAttribution 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectCorneal densitometryes
dc.subjectGraft–host interfacees
dc.subjectDescemet Membrane Endothelial Keratoplasty (DMEK)es
dc.subjectDescemet Stripping Automated Endothelial Keratoplasty (DSAEK)es
dc.titleScheimpflug Corneal Densitometry Patterns at the Graft–Host Interface in DMEK and DSAEK: A 12-Month Longitudinal Comparative Studyes
dc.typeinfo:eu-repo/semantics/articlees
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Física de la Materia Condensadaes
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Cirugíaes
dc.relation.publisherversionhttps://doi.org/10.3390/jcm12227133es
dc.identifier.doi10.3390/jcm12227133es
dc.journaltitleJournal of Clinical Medicinees
dc.publication.volumen12es
dc.publication.issue22es
dc.publication.initialPage7133es

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