dc.creator | Rubio-Manzanares-Dorado, Mercedes | es |
dc.creator | Álamo Martínez, José María | es |
dc.creator | Bernal Bellido, Carmen | es |
dc.creator | Marín Gómez, Luis Miguel | es |
dc.creator | Suárez Artacho, Gonzalo | es |
dc.creator | Cepeda Franco, Carmen | es |
dc.creator | Wang, Jize | es |
dc.creator | Gómez Bravo, Miguel Ángel | es |
dc.creator | Padillo Ruiz, Francisco Javier | es |
dc.date.accessioned | 2024-05-21T14:33:15Z | |
dc.date.available | 2024-05-21T14:33:15Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Rubio-Manzanares-Dorado, M., Álamo Martínez, J.M., Bernal Bellido, C., Marín Gómez, L.M., Suárez Artacho, G., Cepeda Franco, C.,...,Padillo Ruiz, F.J. (2017). Post-transplant lymphoproliferative disease in liver transplant recipients. Revista Española de Enfermedades Digestivas, 109 (6), 406-412. https://doi.org/10.17235/reed.2017.4228/2016. | |
dc.identifier.issn | 1130-0108 | es |
dc.identifier.issn | 2340-4167 | es |
dc.identifier.uri | https://hdl.handle.net/11441/158762 | |
dc.description.abstract | Introduction: Post-transplant lymphoproliferative syndrome
(PTLD) is a rare and potentially life-threatening complication after
liver transplantation. The aim of this study was to analyze the
clinicopathologic features related to PTLD in a single institution
after liver transplantation.
Methods: Observational study where we have retrospectively
analyzed 851 cases who underwent liver transplantation. Ten cases
have developed PTLD. Their clinical-pathological characteristics
and the treatment received have been analyzed.
Results: PTLD incidence was 1.2% (10/851). The mean time
from liver transplantation to PTLD diagnosis was 36 months (range
1.2 to 144 months). PTLD localization was extranodal in all cases,
the most frequent location being intestinal. Seven cases showed
a monomorphic lymphoma which in all cases was differentiated
B cell lymphomas. Fifty per cent of the series were seropositive
for Epstein-Barr virus. Five patients were alive at the time of the
review. Among these patients, we observed three cases of complete
remission and two cases of disease stabilization. The death rate was
higher in the first year after diagnosis of PTLD.
Conclusion: PTLD is a rare complication after liver
transplantation, but it may pose a threat to the life of a liver
transplant recipient. It is essential to identify patients at risk, to
establish an early diagnosis and treatment that can change the
outcome of the disease. | es |
dc.format | application/pdf | es |
dc.format.extent | 7 p. | es |
dc.language.iso | eng | es |
dc.publisher | Aran Ediciones S.A. | es |
dc.relation.ispartof | Revista Española de Enfermedades Digestivas, 109 (6), 406-412. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Post-transplant lymphoproliferative disease | es |
dc.subject | Liver transplantation | es |
dc.subject | Rituximab | es |
dc.title | Post-transplant lymphoproliferative disease in liver transplant recipients | es |
dc.type | info:eu-repo/semantics/article | es |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Cirugía | es |
dc.relation.publisherversion | https://www.reed.es/ArticuloFicha.aspx?id=1109&hst=0&idR=49&tp=1 | es |
dc.identifier.doi | 10.17235/reed.2017.4228/2016 | es |
dc.journaltitle | Revista Española de Enfermedades Digestivas | es |
dc.publication.volumen | 109 | es |
dc.publication.issue | 6 | es |
dc.publication.initialPage | 406 | es |
dc.publication.endPage | 412 | es |