Artículo
Drug Loaded Implantable Devices to Treat Cardiovascular Disease
Autor/es | Adhami, Masoud
Martin, Niamh K. Maguire, Ciara Courtenay, Aaron J. Donnelly, Ryan F. Domínguez Robles, Juan Larrañeta, Eneko |
Departamento | Universidad de Sevilla. Departamento de Farmacia y Tecnología Farmacéutica |
Fecha de publicación | 2023 |
Fecha de depósito | 2024-03-01 |
Publicado en |
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Resumen | Introduction: It is widely acknowledged that cardiovascular diseases (CVDs) continue to be the leading cause of death globally. Furthermore, CVDs are the leading cause of diminished quality of life for patients, frequently ... Introduction: It is widely acknowledged that cardiovascular diseases (CVDs) continue to be the leading cause of death globally. Furthermore, CVDs are the leading cause of diminished quality of life for patients, frequently as a result of their progressive deterioration. Medical implants that release drugs into the body are active implants that do more than just provide mechanical support; they also have a therapeutic role. Primarily, this is achieved through the controlled release of active pharmaceutical ingredients (API) at the implementation site. Areas covered: In this review, the authors discuss drug-eluting stents, drug-eluting vascular grafts, and drug-eluting cardiac patches with the aim of providing a broad overview of the three most common types of cardiac implant. Expert opinion: Drug eluting implants are an ideal alternative to traditional drug delivery because they allow for accurate drug release, local drug delivery to the target tissue, and minimize the adverse side effects associated with systemic administration. Despite the fact that there are still challenges that need to be addressed, the ever-evolving new technologies are making the fabrication of drug-eluting implants a rewarding therapeutic endeavor with the possibility for even greater advances. |
Agencias financiadoras | Ministerio de Ciencia e Innovación (MICIN). España |
Identificador del proyecto | RYC-2021-034357- |
Cita | Adhami, M., Martin, N.K., Maguire, C., Courtenay, A.J., Donnelly, R.F., Domínguez Robles, J. y Larrañeta, E. (2023). Drug Loaded Implantable Devices to Treat Cardiovascular Disease. Expert Opinion on Drug Delivery, 20 (4), 507-522. https://doi.org/10.1080/17425247.2023.2190580. |
Ficheros | Tamaño | Formato | Ver | Descripción |
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Drug loaded implantable.pdf | 9.272Mb | [PDF] | Ver/ | |