dc.creator | Sanz Herrera, José Antonio | es |
dc.creator | Reina Romo, Esther | es |
dc.creator | Boccaccini, Aldo R. | es |
dc.date.accessioned | 2024-01-24T17:31:56Z | |
dc.date.available | 2024-01-24T17:31:56Z | |
dc.date.issued | 2018-03 | |
dc.identifier.citation | Sanz-Herrera, J.A., Reina-Romo, E. y Boccaccini, A.R. (2018). In silico design of magnesium implants: Macroscopic modelling. Journal of the Mechanical Behavior of Biomedical Materials, 79, 181-188. https://doi.org/10.1016/j.jmbbm.2017.12.016. | |
dc.identifier.issn | 1751-6161 | es |
dc.identifier.uri | https://hdl.handle.net/11441/153941 | |
dc.description.abstract | Magnesium-based biomedical implants offer many advantages versus traditional ones although some challenges are still present. In this context, mathematical modeling and computational simulation may be a useful and complementary tool to evaluate in silico the performance of magnesium biomaterials under different conditions. In this paper, a phenomenologically-based model to simulate magnesium corrosion is developed. The model describes the physico-chemical interactions and evolution of species present in this phenomenon. A set of 7 species is considered in the model, which allows to simulate hydrogen release, pH evolution, corrosion products formation as well as degradation of magnesium. The model is developed under the continuum media theory and is implemented in a finite element framework. In the results section, the effect of model parameters on outcomes is firstly explored. Second, model results are qualitative validated versus two examples of application found in the literature. Two main conclusions are derived from this work: (i) the model captures well the experimental trends and allows to analyze the main variables present in magnesium corrosion, (ii) even though further validation is needed the model may be a useful standard in the design of degradable metal implants. | es |
dc.description.sponsorship | Ministerio de Economía y Competitividad DPI2014-58233-P | es |
dc.format | application/pdf | es |
dc.format.extent | 8 p. | es |
dc.language.iso | eng | es |
dc.publisher | Elsevier | es |
dc.relation.ispartof | Journal of the Mechanical Behavior of Biomedical Materials, 79, 181-188. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Magnesium implants | es |
dc.subject | Biodegradable metals | es |
dc.subject | Tissue Engineering | es |
dc.subject | Mathematical modeling | es |
dc.subject | Computational simulation | es |
dc.title | In silico design of magnesium implants: Macroscopic modelling | es |
dc.type | info:eu-repo/semantics/article | es |
dc.type.version | info:eu-repo/semantics/acceptedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Mecánica de Medios Continuos y Teoría de Estructuras | es |
dc.relation.projectID | DPI2014-58233-P | es |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S1751616117305593 | es |
dc.identifier.doi | 10.1016/j.jmbbm.2017.12.016 | es |
dc.contributor.group | Universidad de Sevilla. TEP245: Ingeniería de las Estructuras | es |
dc.journaltitle | Journal of the Mechanical Behavior of Biomedical Materials | es |
dc.publication.volumen | 79 | es |
dc.publication.initialPage | 181 | es |
dc.publication.endPage | 188 | es |
dc.contributor.funder | Ministerio de Economía y Competitividad (MINECO). España | es |