dc.creator | Gil González, Irene | es |
dc.creator | Pérez San Gregorio, María de los Ángeles | es |
dc.creator | Conrad, Rupert | es |
dc.creator | Martín Rodríguez, Agustín | es |
dc.date.accessioned | 2023-12-11T14:54:34Z | |
dc.date.available | 2023-12-11T14:54:34Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Gil González, I., Pérez San Gregorio, Á., Conrad, R. y Martín Rodríguez, A. (2021). Predicting improvement of quality of life and mental health over 18-months in multiple sclerosis patients. Multiple Sclerosis and Related Disorders, 53, 103093. https://doi.org/10.1016/j.msard.2021.103093. | |
dc.identifier.issn | 2211-0348 (impreso) | es |
dc.identifier.issn | 2211-0356 (electrónico) | es |
dc.identifier.uri | https://hdl.handle.net/11441/152364 | |
dc.description.abstract | Background : Multiple sclerosis (MS) is a chronic neurodegenerative disease that can
negatively affect functioning across a wide spectrum of domains. This study aims to
investigate the development of mental health and quality of life in MS patients over 18-
months and to identify predictive factors.
Method : 314 MS outpatients of Virgen Macarena University Hospital in Sevilla/Spain
(mean age 45 years, 67.8% women, on average 12.1 years since diagnosis)
participated in the study. Health-related quality of life (HRQOL) and mental health were
assessed by the 12-Item Short Form Health Survey (SF-12) and the General Health
Questionnaire-28 (GHQ-28) twice over an 18-months follow up period.
Results : HRQOL and mental health significantly improved in almost all domains,
except for a worsening of vitality. Mental and physical HRQOL improved by a large
effect size. Binomial logistic regression models showed that disability status (Expanded
Disability Status Scale) predicted both components of HRQOL and age the physical
component of HRQOL. Sex, educational level, and disease duration predicted mental
health.
Conclusions : Our findings confirm the possibility of a significant large-sized
improvement of HRQOL in the course of 18-months even 12 years after MS diagnosis
on average. The study showed the importance of sociodemographic as well as clinical
variables to predict HRQOL and mental health. Further longitudinal research is needed
to better understand their impact on patients’ outcomes. | es |
dc.description.sponsorship | Ministerio de Educación, Cultura y Deporte (MECD) de España FPU 17/04240 | |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Elsevier | es |
dc.relation.ispartof | Multiple Sclerosis and Related Disorders, 53, 103093. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Multiple sclerosis | es |
dc.subject | Quality of life | es |
dc.subject | Mental health | es |
dc.subject | Risk factors | es |
dc.title | Predicting improvement of quality of life and mental health over 18-months in multiple sclerosis patients | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/acceptedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Personalidad, Evaluación y Tratamiento Psicológicos | es |
dc.relation.projectID | FPU 17/04240 | |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S2211034821003606?via%3Dihub | es |
dc.identifier.doi | 10.1016/j.msard.2021.103093 | es |
dc.journaltitle | Multiple Sclerosis and Related Disorders | es |
dc.publication.volumen | 53 | es |
dc.publication.initialPage | 103093 | es |
dc.contributor.funder | Ministerio de Educación, Cultura y Deporte (MECD). España | |