dc.creator | Escudero Cuadrado, Luis María | es |
dc.creator | Tagua Jáñez, Antonio | es |
dc.creator | Schamberger, Barbara | es |
dc.creator | Ziege, Ricardo | es |
dc.creator | Anselme, Karine | es |
dc.creator | Ben Amar, Martine | es |
dc.creator | Bykowski, Michał | es |
dc.creator | Castro, André P.G | es |
dc.creator | Dunlop, John W.C | es |
dc.date.accessioned | 2023-08-03T08:19:46Z | |
dc.date.available | 2023-08-03T08:19:46Z | |
dc.date.issued | 2023-03-29 | |
dc.identifier.citation | Escudero Cuadrado, L.M., Tagua Jáñez, A., Schamberger, B., Ziege, R., Anselme, K., Ben Amar, M.,...,Dunlop, J.W.C. (2023). Curvature in Biological Systems: Its Quantification, Emergence, and Implications across the Scales. Advanced Materials, 35 (13). https://doi.org/10.1002/adma.202206110. | |
dc.identifier.issn | 0935-9648 | es |
dc.identifier.issn | 1521-4095 | es |
dc.identifier.uri | https://hdl.handle.net/11441/148375 | |
dc.description.abstract | Surface curvature both emerges from, and influences the behavior of, living objects at length scales ranging from cell membranes to single cells to tissues and organs. The relevance of surface curvature in biology is supported by numerous experimental and theoretical investigations in recent years. In this review, first, a brief introduction to the key ideas of surface curvature in the context of biological systems is given and the challenges that arise when measuring surface curvature are discussed. Giving an overview of the emergence of curvature in biological systems, its significance at different length scales becomes apparent. On the other hand, summarizing current findings also shows that both single cells and entire cell sheets, tissues or organisms respond to curvature by modulating their shape and their migration behavior. Finally, the interplay between the distribution of morphogens or micro-organisms and the emergence of curvature across length scales is addressed with examples demonstrating these key mechanistic principles of morphogenesis. Overall, this review highlights that curved interfaces are not merely a passive by-product of the chemical, biological, and mechanical processes but that curvature acts also as a signal that co-determines these processes. © 2023 The Authors. Advanced Materials published by Wiley-VCH GmbH. | es |
dc.description.sponsorship | Fundação para a Ciência e Tecnologia. Portugal UIDB/50022/2020, 2020.04417 | es |
dc.description.sponsorship | Luxembourg National Research Fund A17/MS/11572821/MBRACE | es |
dc.description.sponsorship | European Research Council (ERC) 851960 | es |
dc.description.sponsorship | Netherlands Organization for Scientific Research 024.003.013 | es |
dc.description.sponsorship | French National Research Agency ANR-201-8-CE1-3-0008 | es |
dc.description.sponsorship | Australian Research Council DP200102593 | es |
dc.description.sponsorship | Deutsche Forschungsgemeinschaft (DFG) CI 203/-2 1 | es |
dc.description.sponsorship | Ministerio de Ciencia e Innovación (MICIN). España PID2021- 123013O-BI00 | es |
dc.format | application/pdf | es |
dc.format.extent | 23 p. | es |
dc.language.iso | eng | es |
dc.publisher | John Wiley and Sons Inc | es |
dc.relation.ispartof | Advanced Materials, 35 (13). | |
dc.rights | Atribución-NoComercial 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | * |
dc.subject | Biological systems | es |
dc.subject | Mechanotransduction | es |
dc.subject | Morphogenesis | es |
dc.subject | Surface curvature | es |
dc.title | Curvature in Biological Systems: Its Quantification, Emergence, and Implications across the Scales | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Biología Celular | es |
dc.relation.projectID | 2020.04417 | es |
dc.relation.projectID | A17/MS/11572821/MBRACE | es |
dc.relation.projectID | 851960 | es |
dc.relation.projectID | 024.003.013 | es |
dc.relation.projectID | ANR-201-8-CE1-3-0008 | es |
dc.relation.projectID | DP200102593 | es |
dc.relation.projectID | CI 203/-2 1 | es |
dc.relation.projectID | PID2021- 123013O-BI00 | es |
dc.relation.publisherversion | https://doi.org/10.1002/adma.202206110 | es |
dc.identifier.doi | 10.1002/adma.202206110 | es |
dc.journaltitle | Advanced Materials | es |
dc.publication.volumen | 35 | es |
dc.publication.issue | 13 | es |
dc.contributor.funder | Fundação para a Ciência e a Tecnologia. Portugal | es |
dc.contributor.funder | Luxembourg National Research Fund | es |
dc.contributor.funder | European Research Council (ERC) | es |
dc.contributor.funder | Netherlands Organization for Scientific Research | es |
dc.contributor.funder | French National Research Agency | es |
dc.contributor.funder | Australian Research Council | es |
dc.contributor.funder | Deutsche Forschungsgemeinschaft (DFG) | es |
dc.contributor.funder | Ministerio de Ciencia e Innovación (MICIN). España | es |