dc.creator | Callejón-Leblic, María A. | es |
dc.creator | Martín-Jiménez, Daniel Iván | es |
dc.creator | Moreno Luna, Ramón | es |
dc.creator | Palacios García, José M. | es |
dc.creator | Álvarez Cendrero, M. | es |
dc.creator | Vizcarra Melgar, Julissa A. | es |
dc.creator | Maza Solano, Juan Manuel | es |
dc.creator | Tena García, Beatriz | es |
dc.creator | Sánchez Gómez, Serafín | es |
dc.date.accessioned | 2023-07-06T13:11:00Z | |
dc.date.available | 2023-07-06T13:11:00Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | Callejón-Leblic, M.A., Martín-Jiménez, D.I., Moreno Luna, R., Palacios García, J.M., Álvarez Cendrero, M., Vizcarra Melgar, J.A.,...,Sánchez Gómez, S. (2022). Analysis of Prevalence and Predictive Factors of Long-Lasting Olfactory and Gustatory Dysfunction in COVID-19 Patients. Life, 12 (8), 1256. https://doi.org/10.3390/life12081256. | |
dc.identifier.issn | 2075-1729 | es |
dc.identifier.uri | https://hdl.handle.net/11441/147775 | |
dc.description.abstract | Background: Although smell and taste disorders are highly prevalent symptoms of COVID 19 infection, the predictive factors leading to long-lasting chemosensory dysfunction are still poorly
understood. Methods: 102 out of 421 (24.2%) mildly symptomatic COVID-19 patients completed
a second questionnaire about the evolution of their symptoms one year after the infection using
visual analog scales (VAS). A subgroup of 69 patients also underwent psychophysical evaluation of
olfactory function through UPSIT. Results: The prevalence of chemosensory dysfunction decreased
from 82.4% to 45.1% after 12 months, with 46.1% of patients reporting a complete recovery. Patients
older than 40 years (OR = 0.20; 95% CI: [0.07, 0.56]) and with a duration of loss of smell longer
than four weeks saw a lower odds ratio for recovery (OR = 0.27; 95% CI: [0.10, 0.76]). In addition,
28 patients (35.9%) reported suffering from parosmia, which was associated with moderate to severe
taste dysfunction at the baseline (OR = 7.80; 95% CI: [1.70, 35.8]). Among the 69 subjects who
underwent the UPSIT, 57 (82.6%) presented some degree of smell dysfunction, showing a moderate
correlation with self-reported VAS (r = −0.36, p = 0.0027). Conclusion: A clinically relevant number
of subjects reported persistent chemosensory dysfunction and parosmia one year after COVID-19
infection, with a moderate correlation with psychophysical olfactory tests. | es |
dc.format | application/pdf | es |
dc.format.extent | 17 p. | es |
dc.language.iso | eng | es |
dc.publisher | MDPI AG | es |
dc.relation.ispartof | Life, 12 (8), 1256. | |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Olfactory disorders | es |
dc.subject | COVID-19 | es |
dc.subject | Prediction model | es |
dc.subject | Anosmia | es |
dc.subject | Parosmia | es |
dc.subject | Smell disorders | es |
dc.subject | Smell test | es |
dc.title | Analysis of Prevalence and Predictive Factors of Long-Lasting Olfactory and Gustatory Dysfunction in COVID-19 Patients | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Cirugía | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Enfermería | es |
dc.relation.publisherversion | https://www.mdpi.com/2075-1729/12/8/1256 | es |
dc.identifier.doi | 10.3390/life12081256 | es |
dc.journaltitle | Life | es |
dc.publication.volumen | 12 | es |
dc.publication.issue | 8 | es |
dc.publication.initialPage | 1256 | es |
dc.contributor.funder | Junta de Andalucía | es |
dc.contributor.funder | Fondo Europeo de Desarrollo Regional (FEDER) | es |