dc.creator | Tristancho Pérez, Ángela | es |
dc.creator | Villalba Moreno, Ángela | es |
dc.creator | Santos Rubio, María Dolores | es |
dc.creator | Belda Rustarazo, Susana | es |
dc.creator | Santos Ramos, Bernardo | es |
dc.creator | Sánchez Fidalgo, Susana | es |
dc.date.accessioned | 2023-05-02T13:18:37Z | |
dc.date.available | 2023-05-02T13:18:37Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | Tristancho Pérez, Á., Villalba Moreno, Á., Santos Rubio, M.D., Belda Rustarazo, S., Santos-Ramos, B. y Sánchez Fidalgo, S. (2022). Concordance Among 10 Different Anticholinergic Burden Scales in At-Risk Older Populations. Journal of Patient Safety, 18 (4), e816-e821. https://doi.org/10.1097/PTS.0000000000000929. | |
dc.identifier.issn | 1549-8425 | es |
dc.identifier.issn | 1549-8417 | es |
dc.identifier.uri | https://hdl.handle.net/11441/144933 | |
dc.description.abstract | Objective: The aim of the study was to evaluate the concordance among
10 anticholinergic scales for the measurement of anticholinergic drug ex posure in at-risk elderly complex chronic patients in primary care.
Methods: An 8-month cross-sectional, multicenter study was carried out
in a cohort of complex chronic patients older than 65 years in treatment
with at least 1 drug with anticholinergic activity. Demographic, pharmaco logical, and clinical data were collected. Anticholinergic burden and risk
were detected using the 10 scales included on the anticholinergic burden
calculator (http://www.anticholinergicscales.es/). We used κ statistics to
evaluated the concordance 2 to 2 (according to risk: high, medium, low
or without risk) among the included scales.
Results: Four hundred seventy-three patients were recruited (60.3% fe male, median age of 84 years [interquartile range = 10]). Eighty was the to tal number of anticholinergic drugs with any scale (1197 prescriptions),
with a median of 2 drugs with anticholinergic activity per patient (inter quartile range = 2). The κ statistics comparing all the 10 scales ranged from
−0.175 (Drug Burden Index versus Chew Scale) to 0.708 (Anticholinergic
Activity Scale [AAS] versus Chew Scale). The best concordance was ob tained between AAS and Chew Scale (κ = 0.708), followed by Clinician Rated Anticholinergic Scale and Duran Scale (κ = 0.632) and AAS and
Anticholinergic Cognitive Burden Scale (κ = 0.618), being considered sub stantial strengths of concordance.
Conclusions: The agreement among the 10 scales in elderly patients with
complex chronic conditions was highly variable. Great care should be
taken when assessing anticholinergic drug exposure using existing scales
because of the wide variability among them. The only scales that showed
agreement were the AAS-Chew, Clinician-Rated Anticholinergic Scale–
Duran, and AAS–Anticholinergic Cognitive Burden Scale pairs. In the rest
of the cases, the scales are not interchangeable. | es |
dc.format | application/pdf | es |
dc.format.extent | 6 p. | es |
dc.language.iso | eng | es |
dc.publisher | Ovid Technologies (Wolters Kluwer Health) | es |
dc.relation.ispartof | Journal of Patient Safety, 18 (4), e816-e821. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Anticholinergic agents | es |
dc.subject | Anticholinergic burden scales | es |
dc.subject | Comorbidity | es |
dc.subject | Concordance | es |
dc.subject | Older complex chronic patients | es |
dc.title | Concordance Among 10 Different Anticholinergic Burden Scales in At-Risk Older Populations | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Medicina Preventiva y Salud Pública | es |
dc.relation.publisherversion | https://journals.lww.com/journalpatientsafety/Fulltext/2022/06000/Concordance_Among_10_Different_Anticholinergic.28.aspx | es |
dc.identifier.doi | 10.1097/PTS.0000000000000929 | es |
dc.journaltitle | Journal of Patient Safety | es |
dc.publication.volumen | 18 | es |
dc.publication.issue | 4 | es |
dc.publication.initialPage | e816 | es |
dc.publication.endPage | e821 | es |