Artículo
Oral florid papillomatosis: Topical treatment with 5% imiquimod in orabase
Autor/es | Ruiz Huertas, Pedro
Borrego Luque, Alicia Toledano Valero, Pilar Manzotti, Carolina Rollón Mayordomo, Ángel |
Departamento | Universidad de Sevilla. Departamento de Cirugía |
Fecha de publicación | 2022 |
Fecha de depósito | 2022-12-05 |
Publicado en |
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Resumen | Background: Florid oral papillomatosis is characterized by its tendency to local
recurrence that requires multiple treatments, leading to important functional
sequelae.
Methods: We present 74‐year‐old woman with oral ... Background: Florid oral papillomatosis is characterized by its tendency to local recurrence that requires multiple treatments, leading to important functional sequelae. Methods: We present 74‐year‐old woman with oral florid papillomatosis (OFP) who refused a new surgical treatment, and was treated with imiquimod 5% in orabase on alternate days for 16 weeks. Treatment was complemented with application of hyaluronic acid gel. Results: There were no side effects to the treatment, nor signs of local recurrence, in the treated area at 2 years of follow‐up. Conclusions: After reviewing the literature and according to our knowledge, this is the first published case of oral florid papillomatosis treated topically with imiquimod 5% successfully. Topical treatment with imiquimod 5% in orabase may be a valid alternative for patients with recurrent OFP located in the anterior area of the oral cavity who refuse surgical treatment, although we must closely monitor the patient for the possibility of recurrence or malignant degeneration. |
Cita | Ruiz Huertas, P., Borrego Luque, A., Toledano Valero, P., Manzotti, C. y Rollón Mayordomo, Á. (2022). Oral florid papillomatosis: Topical treatment with 5% imiquimod in orabase. Clinical and experimental dental research, 8 (4), 858-862. https://doi.org/10.1002/cre2.557. |
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