dc.creator | Gaviño-Orduña, J. F. | es |
dc.creator | Caviedes-Bucheli, J. | es |
dc.creator | Manzanares-Céspedes, M. C. | es |
dc.creator | Román-Richón, S. | es |
dc.creator | Martín-Biedma, B. | es |
dc.creator | Segura Egea, Juan José | es |
dc.creator | López-López, J. | es |
dc.date.accessioned | 2022-12-01T16:22:30Z | |
dc.date.available | 2022-12-01T16:22:30Z | |
dc.date.issued | 2021-07-31 | |
dc.identifier.citation | Gaviño-Orduña, J.F., Caviedes-Bucheli, J., Manzanares-Céspedes, M.C., Román-Richón, S., Martín-Biedma, B., Segura Egea, J.J. y López-López, J. (2021). Dentin growth after direct pulp capping with the different fractions of plasma rich in growth factors (PRGF) vs. MAT: experimental study in animal model. Journal of Clinical Medicine, 10 (15), 3432. https://doi.org/10.3390/jcm10153432. | |
dc.identifier.issn | 2077-0383 | es |
dc.identifier.uri | https://hdl.handle.net/11441/140049 | |
dc.description.abstract | Background: This study aimed to evaluate the area of dentin growth in rabbit incisors after
pulp capping with plasma rich in growth factors (PRGF) compared with mineral trioxide aggregate
(MTA) by fluorescence. Methods: twenty-seven upper and lower incisors of rabbits were divided
into 4 groups: poor PRGF (F1) (n = 9 teeth), rich PRGF (F2) (n = 8 teeth), ProRoot MTA (positive
control, n = 5 teeth), and untreated (NC) (negative control, n = 5). Fluorochrome markers were
injected 24 h before surgery and the day before euthanasia, 28 days after the vital pulp therapy
(VPT). Two transverse cuts were performed to every tooth: the first cut (A), 1 mm incisal to the
gingival margin, and the second cut (B), 5 mm apical to the first cut. The sections were assessed
with histomorphometric evaluation by fluorescence microscopy, comparing the dentin area between
fluorescence marks and the total mineralized area. Results: The higher percentage of dentin growth
was observed in the F2 group (B = 63.25%, A = 36.52%), followed by F1 (B = 57.63%, A = 30,12%) and
MTA (B = 38.64%, A = 15.74%). The group with lowest percentage of dentin growth was the NC
group (B = 29.22%, A = 7.82%). Significant difference (p < 0.05) was found between F2 group and
MTA, also statistically significant difference has been observed comparing dentin growth areas of
NC group with F1 and F2 groups. Conclusions: The application of PRGF rich and poor fraction as a
pulp capping material stimulated dentin formation more intensively than MTA and NC. | es |
dc.format | application/pdf | es |
dc.format.extent | 12 p. | es |
dc.language.iso | eng | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | Journal of Clinical Medicine, 10 (15), 3432. | |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Pulp capping | es |
dc.subject | Regenerative endodontics | es |
dc.subject | Pulpotomy | es |
dc.subject | Plasma rich growth factors | es |
dc.subject | Fluorescence microscopy | es |
dc.subject | Vital pulp therapy | es |
dc.title | Dentin growth after direct pulp capping with the different fractions of plasma rich in growth factors (PRGF) vs. MAT: experimental study in animal model | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Estomatología | es |
dc.relation.publisherversion | https://www.mdpi.com/2077-0383/10/15/3432 | es |
dc.identifier.doi | 10.3390/jcm10153432 | es |
dc.journaltitle | Journal of Clinical Medicine | es |
dc.publication.volumen | 10 | es |
dc.publication.issue | 15 | es |
dc.publication.initialPage | 3432 | es |