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dc.creatorGaviño-Orduña, J. F.es
dc.creatorCaviedes-Bucheli, J.es
dc.creatorManzanares-Céspedes, M. C.es
dc.creatorRomán-Richón, S.es
dc.creatorMartín-Biedma, B.es
dc.creatorSegura Egea, Juan Josées
dc.creatorLópez-López, J.es
dc.date.accessioned2022-12-01T16:22:30Z
dc.date.available2022-12-01T16:22:30Z
dc.date.issued2021-07-31
dc.identifier.citationGaviño-Orduña, J.F., Caviedes-Bucheli, J., Manzanares-Céspedes, M.C., Román-Richón, S., Martín-Biedma, B., Segura Egea, J.J. y López-López, J. (2021). Dentin growth after direct pulp capping with the different fractions of plasma rich in growth factors (PRGF) vs. MAT: experimental study in animal model. Journal of Clinical Medicine, 10 (15), 3432. https://doi.org/10.3390/jcm10153432.
dc.identifier.issn2077-0383es
dc.identifier.urihttps://hdl.handle.net/11441/140049
dc.description.abstractBackground: This study aimed to evaluate the area of dentin growth in rabbit incisors after pulp capping with plasma rich in growth factors (PRGF) compared with mineral trioxide aggregate (MTA) by fluorescence. Methods: twenty-seven upper and lower incisors of rabbits were divided into 4 groups: poor PRGF (F1) (n = 9 teeth), rich PRGF (F2) (n = 8 teeth), ProRoot MTA (positive control, n = 5 teeth), and untreated (NC) (negative control, n = 5). Fluorochrome markers were injected 24 h before surgery and the day before euthanasia, 28 days after the vital pulp therapy (VPT). Two transverse cuts were performed to every tooth: the first cut (A), 1 mm incisal to the gingival margin, and the second cut (B), 5 mm apical to the first cut. The sections were assessed with histomorphometric evaluation by fluorescence microscopy, comparing the dentin area between fluorescence marks and the total mineralized area. Results: The higher percentage of dentin growth was observed in the F2 group (B = 63.25%, A = 36.52%), followed by F1 (B = 57.63%, A = 30,12%) and MTA (B = 38.64%, A = 15.74%). The group with lowest percentage of dentin growth was the NC group (B = 29.22%, A = 7.82%). Significant difference (p < 0.05) was found between F2 group and MTA, also statistically significant difference has been observed comparing dentin growth areas of NC group with F1 and F2 groups. Conclusions: The application of PRGF rich and poor fraction as a pulp capping material stimulated dentin formation more intensively than MTA and NC.es
dc.formatapplication/pdfes
dc.format.extent12 p.es
dc.language.isoenges
dc.publisherMDPIes
dc.relation.ispartofJournal of Clinical Medicine, 10 (15), 3432.
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectPulp cappinges
dc.subjectRegenerative endodonticses
dc.subjectPulpotomyes
dc.subjectPlasma rich growth factorses
dc.subjectFluorescence microscopyes
dc.subjectVital pulp therapyes
dc.titleDentin growth after direct pulp capping with the different fractions of plasma rich in growth factors (PRGF) vs. MAT: experimental study in animal modeles
dc.typeinfo:eu-repo/semantics/articlees
dcterms.identifierhttps://ror.org/03yxnpp24
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Estomatologíaes
dc.relation.publisherversionhttps://www.mdpi.com/2077-0383/10/15/3432es
dc.identifier.doi10.3390/jcm10153432es
dc.journaltitleJournal of Clinical Medicinees
dc.publication.volumen10es
dc.publication.issue15es
dc.publication.initialPage3432es

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