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dc.creatorRomero Zaliz, Rocíoes
dc.creatorRubio Escudero, Cristinaes
dc.creatorCordón, Óscares
dc.creatorHarari, Óscares
dc.creatorVal, Coral deles
dc.creatorZwir, Igores
dc.date.accessioned2022-12-01T09:48:53Z
dc.date.available2022-12-01T09:48:53Z
dc.date.issued2006
dc.identifier.citationRomero Zaliz, R., Rubio Escudero, C., Cordón, Ó., Harari, Ó., Val, C.d. y Zwir, I. (2006). Mining Structural Databases: An Evolutionary Multi-Objetive Conceptual Clustering Methodology. En EvoWorkshops 2006: Workshops on Applications of Evolutionary Computation (159-171), Budapest, Hungary: Springer.
dc.identifier.isbn978-3-540-33237-4es
dc.identifier.issn0302-9743es
dc.identifier.urihttps://hdl.handle.net/11441/139993
dc.description.abstractThe increased availability of biological databases contain ing representations of complex objects permits access to vast amounts of data. In spite of the recent renewed interest in knowledge-discovery tech niques (or data mining), there is a dearth of data analysis methods in tended to facilitate understanding of the represented objects and related systems by their most representative features and those relationship de rived from these features (i.e., structural data). In this paper we propose a conceptual clustering methodology termed EMO-CC for Evolution ary Multi-Objective Conceptual Clustering that uses multi-objective and multi-modal optimization techniques based on Evolutionary Algorithms that uncover representative substructures from structural databases. Be sides, EMO-CC provides annotations of the uncovered substructures, and based on them, applies an unsupervised classification approach to retrieve new members of previously discovered substructures. We apply EMO-CC to the Gene Ontology database to recover interesting sub structures that describes problems from different points of view and use them to explain inmuno-inflammatory responses measured in terms of gene expression profiles derived from the analysis of longitudinal blood expression profiles of human volunteers treated with intravenous endo toxin compared to placebo.es
dc.formatapplication/pdfes
dc.format.extent13es
dc.language.isoenges
dc.publisherSpringeres
dc.relation.ispartofEvoWorkshops 2006: Workshops on Applications of Evolutionary Computation (2006), pp. 159-171.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleMining Structural Databases: An Evolutionary Multi-Objetive Conceptual Clustering Methodologyes
dc.typeinfo:eu-repo/semantics/conferenceObjectes
dcterms.identifierhttps://ror.org/03yxnpp24
dc.type.versioninfo:eu-repo/semantics/submittedVersiones
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Lenguajes y Sistemas Informáticoses
dc.relation.publisherversionhttps://link.springer.com/chapter/10.1007/11732242_15es
dc.identifier.doi10.1007/11732242_15es
dc.contributor.groupUniversidad de Sevilla. TIC-254: Data Science and Big Data Labes
dc.publication.initialPage159es
dc.publication.endPage171es
dc.eventtitleEvoWorkshops 2006: Workshops on Applications of Evolutionary Computationes
dc.eventinstitutionBudapest, Hungaryes
dc.relation.publicationplaceBerlin, Germanyes

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