dc.creator | Mayoral, Karina | es |
dc.creator | Garin, Olatz | es |
dc.creator | Lizano-Barrantes, Catalina | es |
dc.creator | Pont, Angels | es |
dc.creator | Caballero-Rabasco, Araceli M. | es |
dc.creator | Praena Crespo, Manuel | es |
dc.creator | Ferrer, Montse | es |
dc.date.accessioned | 2022-11-03T16:48:22Z | |
dc.date.available | 2022-11-03T16:48:22Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | Mayoral, K., Garin, O., Lizano-Barrantes, C., Pont, A., Caballero-Rabasco, A.M., Praena Crespo, M. y Ferrer, M. (2022). Measurement properties of the EQ-5D-Y administered through a smartphone app in children with asthma: a longitudinal questionnaire study. HEALTH AND QUALITY OF LIFE OUTCOMES, 20 (1), 51. https://doi.org/10.1186/s12955-022-01955-5. | |
dc.identifier.issn | 1477-7525 | es |
dc.identifier.uri | https://hdl.handle.net/11441/138682 | |
dc.description.abstract | Background: Asthma impacts children’s physical, emotional, and psychosocial Health-Related Quality of Life (HRQL).
The EQ-5D-Y is a generic econometric instrument developed to measure HRQL in children.
Objective: Evaluation of feasibility, validity, reliability, and responsiveness of EQ-5D-Y descriptive system and util‑
ity index to allow the assessment of HRQL in children with asthma, aged 8–11 years (self-response version) or under
8 years old (proxy-response version).
Methods: We used data from baseline to 10 months of follow-up of an observational, prospective study of children
with persistent asthma recruited by pediatricians in Spain (2018–2020). HRQL instruments were administered through
a smartphone application: ARCA app. The EQ-5D-Y is composed of a 5-dimension descriptive system, a utility index
ranging from 1 to − 0.5392, and a general health visual analogue scale (EQ-VAS). The Pediatric Asthma Impact Scale
(PROMIS-PAIS) includes 8 items, providing a raw score. Construct validity hypotheses were stated a priori, and evalu‑
ated following two approaches, multitrait–multimethod matrix and known groups’ comparisons. Reliability and
responsiveness subsamples were defned by stability or change in EQ-VAS and the Asthma Control Questionnaire
(ACQ), to estimate the intraclass correlation coefcient (ICC) and the magnitude of change over time.
Results: The EQ-5D-Y was completed at baseline for 119 children (81 self-responded and 38 through proxy
response), with a mean age of 9.1 (1.7) years. Mean (SD) of the EQ-5D-Y utility index was 0.93 (0.11), with ceiling and
foor efects of 60.3% and 0%, respectively. Multitrait–multimethod matrix confrmed the associations previously
hypothesized for the EQ-5D-Y utility index [moderate with PROMIS-PAIS (0.38) and weak with ACQ (0.28)], and for the
EQ-5D-Y dimension “problems doing usual activities” [moderate with the ACQ item (0.35) and weak with the PROMIS PAIS item (0.17)]. Statistically signifcant diferences were found in the EQ-5D-Y between groups defned by asthma
control, reliever inhalers use, and second-hand smoke exposure, with mostly moderate efect sizes (0.45–0.75). The ICC of the EQ-5D-Y utility index in the stable subsamples was high (0.81 and 0.79); and responsiveness subsamples
presented a moderate to large magnitude of change (0.68 and 0.78), though without statistical signifcance.
Conclusions: These results support the use of the EQ-5D-Y as a feasible, valid, and reliable instrument for evaluating
HRQL in children with persistent asthma. Further studies are needed on the responsiveness of the EQ-5D-Y in this
population. | es |
dc.format | application/pdf | es |
dc.format.extent | 16 p. | es |
dc.language.iso | eng | es |
dc.publisher | BIOMED CENTRAL LTD | es |
dc.relation.ispartof | HEALTH AND QUALITY OF LIFE OUTCOMES, 20 (1), 51. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Health-Related Quality of Life | es |
dc.subject | Asthma | es |
dc.subject | EQ-5D-Y | es |
dc.subject | Validity | es |
dc.subject | Reliability | es |
dc.subject | Responsiveness | es |
dc.subject | Smartphone app | es |
dc.title | Measurement properties of the EQ-5D-Y administered through a smartphone app in children with asthma: a longitudinal questionnaire study | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Farmacología | es |
dc.relation.projectID | PI15/00449 | es |
dc.relation.projectID | FI16/00071 | es |
dc.relation.publisherversion | https://hqlo.biomedcentral.com/articles/10.1186/s12955-022-01955-5 | es |
dc.identifier.doi | 10.1186/s12955-022-01955-5 | es |
dc.journaltitle | HEALTH AND QUALITY OF LIFE OUTCOMES | es |
dc.publication.volumen | 20 | es |
dc.publication.issue | 1 | es |
dc.publication.initialPage | 51 | es |
dc.contributor.funder | Instituto de Salud Carlos III | es |
dc.contributor.funder | European Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER) | es |