dc.creator | Arjona Valladares, Antonio | es |
dc.creator | Fondevila Estévez, Sabela | es |
dc.creator | Fernández Linsenbarth, Inés | es |
dc.creator | Díez Revuelta, Álvaro | es |
dc.creator | Ruiz Sanz, Francisco Javier | es |
dc.creator | Rodríguez Lorenzana, Alberto | es |
dc.creator | Molina Rodríguez, Vicente | es |
dc.date.accessioned | 2022-10-14T13:56:42Z | |
dc.date.available | 2022-10-14T13:56:42Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Arjona Valladares, A., Fondevila Estévez, S., Fernández Linsenbarth, I., Díez Revuelta, Á., Ruiz Sanz, F.J., Rodríguez Lorenzana, A. y Molina Rodríguez, V. (2021). Event-related potentials associated to N-back test performance in schizophrenia. Progress in Neuropsychopharmacology & Biological Psychiatry, 111. https://doi.org/10.1016/j.pnpbp.2021.110347. | |
dc.identifier.issn | 0278-5846 | es |
dc.identifier.issn | 1878-4216 | es |
dc.identifier.uri | https://hdl.handle.net/11441/137920 | |
dc.description.abstract | Mapping of Event-Related Potentials (ERP) associated with auditory and visual odd-ball paradigms has shown
consistent differences between healthy controls and schizophrenia patients. It may be hypothesized that higher
task attentional/cognitive demand will result in larger differences in these paradigms, which may help understanding the substrates of cognitive deficits in this syndrome. To this aim, we performed an EEG study comparing
the effects of increasing the attentional/cognitive load of an auditory N-back task on the Event-Related Potential
in 50 subjects with schizophrenia (11 first episodes) and 35 healthy controls. We considered a post-target
window of 1000 ms to explore possible between groups differences in N100, P300, and Late Slow Wave
(LSW), and compared these components between 0-back (‘lower attentional/cognitive load) and 1-back (‘higher
attentional/cognitive load’) conditions. Our results showed that N100 and LSW amplitude increase from 0- to 1-
back condition was significantly larger in healthy controls compared to schizophrenia patients. Furthermore,
LSW amplitude difference between 0- and 1-back conditions positively correlated with performance in the
behavioral cognitive assessment. Taken together, these results support that higher task attentional/cognitive load
(0-back vs. 1-back condition) increase N100 amplitude differences and reveal new findings related to the LSW
component in schizophrenia. | es |
dc.format | application/pdf | es |
dc.format.extent | 7 p. | es |
dc.language.iso | eng | es |
dc.publisher | Elsevier | es |
dc.relation.ispartof | Progress in Neuropsychopharmacology & Biological Psychiatry, 111. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Schizophrenia | es |
dc.subject | Event-related potentials | es |
dc.subject | N-back task | es |
dc.subject | Task demands | es |
dc.subject | Attentional/cognitive load | es |
dc.title | Event-related potentials associated to N-back test performance in schizophrenia | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Psicología Experimental | es |
dc.identifier.doi | 10.1016/j.pnpbp.2021.110347 | es |
dc.journaltitle | Progress in Neuropsychopharmacology & Biological Psychiatry | es |
dc.publication.volumen | 111 | es |