Mostrar el registro sencillo del ítem

Artículo

dc.creatorSánchez González, José Maríaes
dc.creatorHita Cantalejo, María Concepción dees
dc.creatorSánchez González, María del Carmenes
dc.date.accessioned2022-10-03T10:45:47Z
dc.date.available2022-10-03T10:45:47Z
dc.date.issued2022
dc.identifier.citationSánchez González, J.M., Hita Cantalejo, M.C.d. y Sánchez González, M.d.C. (2022). Hyaluronic Acid and Galacto-Xyloglucan Eyedrop Efficacy in Young-Adult Oral Contraceptive Users of Childbearing Age. Journal of Clinical Medicine, 11 (15), 154458.
dc.identifier.issn2077-0383es
dc.identifier.urihttps://hdl.handle.net/11441/137555
dc.description.abstractTo assess the efficacy of 0.4% hyaluronic acid and 0.2% galacto-xyloglucan for the subjective symptoms of dry eye disease and tear film invasive and noninvasive signs in 34 young-adult oral contraceptive users of childbearing age, a prospective, longitudinal, single-blind, clinical study was performed in a population of childbearing-age oral-contraceptive consumers. Subjective dry eye disease questionnaires, and invasive and noninvasive tear film assessments were reported before and after six weeks of hyaluronic acid with galacto-xyloglucan (HA-GX) treatment versus hyaluronic acid alone (HA). HA-GX treatment resulted in a greater decrease in the ocular surface disease index (17.01 ± 11.36 score points, p < 0.01) than the HA variation (11.61 ± 11.18 score points, p < 0.01). The standard patient evaluation of eye dryness also decreased more in the HA-GX group (4.06 ± 5.50 score points, p < 0.01) than in the HA alone group (0.70 ± 3.16, p = 0.21). Regarding noninvasive break-up time (NIBUT), the HA-GX group’s first NIBUT achieved an increase of 1.75 ± 1.16 s, p < 0.01, while the HA-alone group increased by only 0.54 ± 1.01 s, p < 0.01. The HA-GX group’s mean NIBUT reported an increase of 3.72 ± 5.69 s, p < 0.01; however, the HA-alone group achieved 2.19 ± 5.26 s, p = 0.05. Hyaluronic acid in combination with galacto-xyloglucan significantly decreased subjective dry eye disease symptoms and increased first and mean NIBUT compared to hyaluronic acid alone. Galacto-xyloglucan added efficacy in young-adult childbearing-age oral contraceptive users.es
dc.formatapplication/pdfes
dc.format.extent12 p.es
dc.language.isoenges
dc.publisherMDPIes
dc.relation.ispartofJournal of Clinical Medicine, 11 (15), 154458.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectdry eye diseasees
dc.subjecthyaluronic acides
dc.subjectgalacto-xyloglucanes
dc.subjectchildbearing agees
dc.subjectoral contraceptiveses
dc.subjecttear filmes
dc.subjecteyedropses
dc.titleHyaluronic Acid and Galacto-Xyloglucan Eyedrop Efficacy in Young-Adult Oral Contraceptive Users of Childbearing Agees
dc.typeinfo:eu-repo/semantics/articlees
dcterms.identifierhttps://ror.org/03yxnpp24
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.relation.publisherversionhttps://dx.doi.org/10.3390/jcm11154458es
dc.identifier.doi10.3390/jcm11154458es
dc.journaltitleJournal of Clinical Medicinees
dc.publication.volumen11es
dc.publication.issue15es
dc.publication.endPage154458es

FicherosTamañoFormatoVerDescripción
pubjcm-11-04458.pdf1.713MbIcon   [PDF] Ver/Abrir  

Este registro aparece en las siguientes colecciones

Mostrar el registro sencillo del ítem

Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Excepto si se señala otra cosa, la licencia del ítem se describe como: Attribution-NonCommercial-NoDerivatives 4.0 Internacional