dc.creator | Asencio Cortés, Gualberto | es |
dc.creator | Aguilar Ruiz, Jesús Salvador | es |
dc.creator | Márquez Chamorro, Alfonso Eduardo | es |
dc.date.accessioned | 2022-05-23T09:05:10Z | |
dc.date.available | 2022-05-23T09:05:10Z | |
dc.date.issued | 2011 | |
dc.identifier.citation | Asencio Cortés, G., Aguilar Ruiz, J.S. y Márquez Chamorro, A.E. (2011). Prediction of protein distance maps by assembling fragments according to physicochemical similarities. En PACBB 2011: 5th International Conference on Practical Applications of Computational Biology and Bioinformatics (271-277), Salamanca, España: Springer. | |
dc.identifier.isbn | 978-3-642-19913-4 | es |
dc.identifier.issn | 1867-5662 | es |
dc.identifier.uri | https://hdl.handle.net/11441/133516 | |
dc.description.abstract | The prediction of protein structures is a current issue of great significance
in structural bioinformatics. More specifically, the prediction of the tertiary structure
of a protein consists of determining its three-dimensional conformation based
solely on its amino acid sequence. This study proposes a method in which protein
fragments are assembled according to their physicochemical similarities, using information
extracted from known protein structures. Many approaches cited in the
literature use the physicochemical properties of amino acids, generally hydrophobicity,
polarity and charge, to predict structure. In our method, implemented with
parallel multithreading, a set of 30 physicochemical amino acid properties selected
from the AAindex database were used. Several protein tertiary structure prediction
methods produce a contact map. Our proposed method produces a distance map,
which provides more information about the structure of a protein than a contact
map. The results of experiments with several non-homologous protein sets demonstrate
the generality of this method and its prediction quality using the amino acid
properties considered. | es |
dc.format | application/pdf | es |
dc.format.extent | 7 | es |
dc.language.iso | eng | es |
dc.publisher | Springer | es |
dc.relation.ispartof | PACBB 2011: 5th International Conference on Practical Applications of Computational Biology and Bioinformatics (2011), pp. 271-277. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.title | Prediction of protein distance maps by assembling fragments according to physicochemical similarities | es |
dc.type | info:eu-repo/semantics/conferenceObject | es |
dc.type.version | info:eu-repo/semantics/submittedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Lenguajes y Sistemas Informáticos | es |
dc.relation.publisherversion | https://link.springer.com/chapter/10.1007/978-3-642-19914-1_36 | es |
dc.identifier.doi | 10.1007/978-3-642-19914-1_36 | es |
dc.contributor.group | Universidad de Sevilla. TIC205: Ingeniería del Software Aplicada | es |
dc.publication.initialPage | 271 | es |
dc.publication.endPage | 277 | es |
dc.eventtitle | PACBB 2011: 5th International Conference on Practical Applications of Computational Biology and Bioinformatics | es |
dc.eventinstitution | Salamanca, España | es |
dc.relation.publicationplace | Berlin, Germany | es |
dc.identifier.sisius | 20131981 | es |