dc.creator | Valdivia Giménez, Victoria Esther | es |
dc.creator | Paggiaro, Chiara | es |
dc.creator | Fernández Fernández, Inmaculada | es |
dc.date.accessioned | 2021-12-22T13:28:24Z | |
dc.date.available | 2021-12-22T13:28:24Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | Valdivia Giménez, V.E., Paggiaro, C. y Fernández Fernández, I. (2019). Synthesis and Characterization of New Biocompatible Amino Amphiphilic Compounds Derived from Oleic Acid as Nanovectors for Drug Delivery. Proceedings, 41 (1), 1. | |
dc.identifier.issn | 2504-3900 | es |
dc.identifier.uri | https://hdl.handle.net/11441/128551 | |
dc.description.abstract | Amphiphilic molecules have been actively explored as promising materials in the field of bio and nanotechnology. These molecules are constituted by a polar head and a lipophilic tail and in an aqueous medium are self-assemble to form different types of macromolecular structures such as micelles, monolayer vesicles, bars, sheets and tubes. In this work, a convergent synthetic approach for the synthesis of two new amphiphilic compounds based on a versatile amino polar head, a tetraethylene glycol spacer and a lipophilic tail derived from oleic acid has been developed. Subsequently, after a self-assembly process in aqueous medium, nanostructures as micelles have been obtained and characterized. Finally, a procedure for the inclusion of the highly lipophilic drug Dexamethasone has been carried out in order to study the ability of these micelles to act as nanovectors for drug delivery. | es |
dc.description.sponsorship | Ministerio de Economía y Competitividad (MEC) CTQ2016- 78580-C2-2-R | es |
dc.format | application/pdf | es |
dc.format.extent | 14 p. | es |
dc.language.iso | eng | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | Proceedings, 41 (1), 1. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | amphiphilic compounds | es |
dc.subject | self-assembly | es |
dc.subject | nanovectors | es |
dc.subject | drug delivery | es |
dc.title | Synthesis and Characterization of New Biocompatible Amino Amphiphilic Compounds Derived from Oleic Acid as Nanovectors for Drug Delivery | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Química Orgánica y Farmacéutica | es |
dc.relation.projectID | CTQ2016-78580-C2-2-R | es |
dc.relation.publisherversion | https://doi.org/10.3390/ecsoc-23-06458 | es |
dc.identifier.doi | 10.3390/ecsoc-23-06458 | es |
dc.journaltitle | Proceedings | es |
dc.publication.volumen | 41 | es |
dc.publication.issue | 1 | es |
dc.publication.initialPage | 1 | es |
dc.contributor.funder | Ministerio de Economía y Competitividad (MINECO). España | es |