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Mostrando ítems 1-10 de 10
Artículo
Special Issue on “Biomaterials for Bone Tissue Engineering”
(MDPI, 2020-04)
The present Special Issue covers recent advances in the field of tissue engineering applied to bone tissue. Bone tissue engineering is a wide research topic, so di erent works from di erent transversal areas of research ...
Artículo
A multiscale data-driven approach for bone tissue biomechanics
(Elsevier, 2020-08)
The data-driven methodology with application to continuum mechanics relies upon two main pillars: (i) experimental characterization of stress–strain pairs associated to different loading states, and (ii) numerical elaboration ...
Artículo
Analysis of the parametric correlation in mathematical modeling of In vitro glioblastoma evolution using copulas
(MDPI, 2021)
Modeling and simulation are essential tools for better understanding complex biological processes, such as cancer evolution. However, the resulting mathematical models are often highly non-linear and include many parameters, ...
Artículo
A new reliability-based data-driven approach for noisy experimental data with physical constraints
(Elsevier, 2018-01)
Data Science has burst into simulation-based engineering sciences with an impressive impulse. However, data are never uncertainty-free and a suitable approach is needed to face data measurement errors and their intrinsic ...
Artículo
In silico dynamic characterization of the femur: Physiological versus mechanical boundary conditions
(Elsevier, 2018-08)
It is established that bone tissue adapts and responds to mechanical loading. Several studies have suggested an existence of positive influence of vibration on the bone mass maintenance. Thus, some bone regeneration therapies ...
Artículo
Model of dissolution in the framework of tissue engineering and drug delivery
(Springer, 2018-10)
Dissolution phenomena are ubiquitously present in biomaterials in many different fields. Despite the advantages of simulation-based design of biomaterials in medical applications, additional efforts are needed to derive ...
Artículo
Advanced in silico validation framework for three-dimensional Traction Force Microscopy and application to an in vitro model of sprouting angiogenesis
(Elsevier, 2021-05)
In the last decade, cellular forces in three-dimensional hydrogels that mimic the extracellular matrix have been calculated by means of Traction Force Microscopy (TFM). However, characterizing the accuracy limits of a ...
Artículo
In silico design of magnesium implants: Macroscopic modelling
(Elsevier, 2018-03)
Magnesium-based biomedical implants offer many advantages versus traditional ones although some challenges are still present. In this context, mathematical modeling and computational simulation may be a useful and complementary ...
Artículo
Multiscale Characterisation of Cortical Bone Tissue
(MDPI, 2019-12)
Multiscale analysis has become an attractive technique to predict the behaviour of materials whose microstructure strongly changes spatially or among samples, with that microstructure controlling the local constitutive ...
Artículo
An unsupervised data completion method for physically-based data-driven models
(Elsevier, 2019-02)
Data-driven methods are an innovative model-free approach for engineering and sciences, still in process of maturation. The idea behind is the combination of data analytics techniques, to handle the huge amount of data ...