• Artículo
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      A comparison of effort estimation methods for 4GL programs: experiences with Statistics and Data Mining 

      Riquelme Santos, José Cristóbal; Polo, Macario; Aguilar Ruiz, Jesús Salvador; Piattini Velthuis, Mario; Ferrer Troyano, Francisco Javier; Ruiz, Francisco (World Scientific Publishing Company, 2006)
      This paper presents an empirical study analysing the relationship between a set of metrics for Fourth–Generation Languages ...
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      A decision tree-based method for protein contact map prediction 

      Santiesteban Toca, Cosme E.; Márquez Chamorro, Alfonso Eduardo; Asencio Cortés, Gualberto; Aguilar Ruiz, Jesús Salvador (Springer, 2011)
      In this paper, we focus on protein contact map prediction. We describe a method where contact maps are predicted using ...
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      A Deterministic Model to Infer Gene Networks from Microarray Data 

      Nepomuceno Chamorro, Isabel de los Ángeles; Aguilar Ruiz, Jesús Salvador; Díaz Díaz, Norberto; Rodríguez Baena, Domingo S.; García Gutiérrez, Jorge (Springer, 2007)
      Microarray experiments help researches to construct the str ucture of gene regulatory networks, i.e., networks representing ...
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      A Hybrid Metaheuristic for Biclustering Based on Scatter Search and Genetic Algorithms 

      Nepomuceno Chamorro, Juan Antonio; Troncoso Lora, Alicia; Aguilar Ruiz, Jesús Salvador (Springer, 2009)
      In this paper a hybrid metaheuristic for biclustering based on Scatter Search and Genetic Algorithms is presented. A ...
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      A Local Search in Scatter Search for Improving Biclusters 

      Nepomuceno Chamorro, Juan Antonio; Troncoso Lora, Alicia; Aguilar Ruiz, Jesús Salvador (IEEE Computer Society, 2011)
      Scatter Search is a population-based metaheuristic that emphasizes systematic processes against random proce dures. A ...
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      A Measure for Data Set Editing by Ordered Projections 

      Aguilar Ruiz, Jesús Salvador; Nepomuceno Chamorro, Juan Antonio; Díaz Díaz, Norberto; Nepomuceno Chamorro, Isabel de los Ángeles (Springer, 2006)
      In this paper we study a measure, named weakness of an example, which allows us to establish the importance of an example ...
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      A Multi-objective Genetic Algorithm for the Protein Structure Prediction 

      Márquez Chamorro, Alfonso Eduardo; Divina, Federico; Aguilar Ruiz, Jesús Salvador; Asencio Cortés, Gualberto (IEEE Computer Society, 2011)
      The Protein Structure Prediction (PSP) problem consists of predicting the structure of a protein from its amino acids ...
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      A Nearest Neighbour-Based Approach for Viral Protein Structure Prediction 

      Asencio Cortés, Gualberto; Aguilar Ruiz, Jesús Salvador; Márquez Chamorro, Alfonso Eduardo (Springer, 2011)
      Protein tertiary structure prediction consists of determining the three-dimensional conformation of a protein based solely ...
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      A novel approach for avoiding overlapping among biclusters in expression data 

      Pontes Balanza, Beatriz; Divina, Federico; Gíraldez, Raúl; Aguilar Ruiz, Jesús Salvador (IEEE Computer Society, 2008)
      Biclustering is a technique used in analysis of microarray data. It aims at discovering subsets of genes that presents ...
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      A NSGA-II Algorithm for the Residue-Residue Contact Prediction 

      Márquez Chamorro, Alfonso Eduardo; Divina, Federico; Aguilar Ruiz, Jesús Salvador; Bacardit, Jaume; Asencio Cortés, Gualberto; Santiesteban Toca, Cosme E. (Springer, 2012)
      We present a multi-objective evolutionary approach to predict protein contact maps. The algorithm provides a set of ...
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      Alpha Helix Prediction Based on Evolutionary Computation 

      Márquez Chamorro, Alfonso Eduardo; Divina, Federico; Aguilar Ruiz, Jesús Salvador; Asencio Cortés, Gualberto (Springer, 2010)
      Multiple approaches have been developed in order to predict the protein secondary structure. In this paper, we propose ...
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      An Approach to Reduce the Cost of Evaluation in Evolutionary Learning 

      Giráldez, Raúl; Díaz Díaz, Norberto; Nepomuceno Chamorro, Isabel de los Ángeles; Aguilar Ruiz, Jesús Salvador (Springer, 2005)
      The supervised learning methods applying evolutionary al gorithms to generate knowledge model are extremely costly in time ...
    • Artículo
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      An effective measure for assessing the quality of biclusters 

      Divina, Federico; Pontes Balanza, Beatriz; Giráldez, Raúl; Aguilar Ruiz, Jesús Salvador (Elsevier, 2012)
      Biclustering is becoming a popular technique for the study of gene expression data. This is mainly due to the capability ...
    • Capítulo de Libro
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      An efficient data structure for decision rules discovery 

      Giráldez Rojo, Raúl; Aguilar Ruiz, Jesús Salvador; Riquelme Santos, José Cristóbal (2003)
      The increasing amount of information available is encouraging the search for efficient techniques to improve the data ...
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      An efficient decision rule-based system for the protein residue-residue contact prediction 

      Márquez Chamorro, Alfonso Eduardo; Divina, Federico; Bacardit, Jaume; Aguilar Ruiz, Jesús Salvador (IEEE Computer Society, 2013)
      Protein structure prediction remains one of the most important challenges in molecular biology. Contact maps have been ...
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      An Efficient Nearest Neighbor Method for Protein Contact Prediction 

      Asencio Cortés, Gualberto; Aguilar Ruiz, Jesús Salvador; Márquez Chamorro, Alfonso Eduardo (Springer, 2015)
      A variety of approaches for protein inter-residue contact pre diction have been developed in recent years. However, this ...
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      An Evolutionary Approach for Protein Contact Map Prediction 

      Márquez Chamorro, Alfonso Eduardo; Divina, Federico; Aguilar Ruiz, Jesús Salvador; Asencio Cortés, Gualberto (Springer, 2011)
      In this study, we present a residue-residue contact prediction approach based on evolutionary computation. Some amino acid ...
    • Artículo
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      An evolutionary approach to estimating software development projects 

      Aguilar Ruiz, Jesús Salvador; Ramos Román, Isabel; Riquelme Santos, José Cristóbal; Toro Bonilla, Miguel (Elsevier, 2001)
      The use of dynamic models and simulation environments in connection with software projects paved the way for tools that ...
    • Ponencia
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      An Overlapping Control–Biclustering Algorithm from Gene Expression Data 

      Nepomuceno Chamorro, Juan Antonio; Troncoso Lora, Alicia; Aguilar Ruiz, Jesús Salvador (IEEE Computer Society, 2009)
      In this paper a hybrid metaheuristic for biclustering based on Scatter Search and Genetic Algorithms is pre sented. A ...
    • Capítulo de Libro
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      Analysis of Feature Rankings for Classification 

      Ruiz Sánchez, Roberto; Aguilar Ruiz, Jesús Salvador; Riquelme Santos, José Cristóbal; Díaz Díaz, Norberto (2005)
      Different ways of contrast generated rankings by feature selection algorithms are presented in this paper, showing several ...