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Artículo
Crosstalk between chromatin structure, cohesin activity and transcription
(BMC (part of Springer Nature), 2019)
Background: A complex interplay between chromatin and topological machineries is critical for genome architec‑ ture and function. However, little is known about these reciprocal interactions, even for cohesin, despite its ...
Artículo
Histone depletion prevents telomere fusions in pre-senescent cells
(Public Library of Science, 2018-06-07)
Upon telomerase inactivation, telomeres gradually shorten with each cell division until cells enter replicative senescence. In Saccharomyces cerevisiae, the kinases Mec1/ATR and Tel1/ATM protect the genome during pre-senescence ...