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Artículo
Editorial: Molecular chaperones and neurodegeneration
(Frontiers Media, 2017)
Artículo
Commentary: Immunochemical Markers of the Amyloid Cascade in the Hippocampus in Motor Neuron Diseases
(Frontiers Media, 2017)
In case we needed reminding, age-related neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and motor neurone disease (MND) have two factors in common: (i) advancing age as the single ...
Artículo
Conditional deletion of WT1 in the septum transversum mesenchyme causes congenital diaphragmatic hernia in mice
(eLife Sciences Publications, 2016)
Congenital diaphragmatic hernia (CDH) is a severe birth defect. Wt1-null mouse embryos develop CDH but the mechanisms regulated by WT1 are unknown. We have generated a murine model with conditional deletion of WT1 in the ...
Artículo
A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice
(Ferrata Storti Foundation, 2017)
GATA transcription factors are expressed in the mesoderm and endoderm during development. GATA1-3, but not GATA4, are critically involved in hematopoiesis. An enhancer (G2) of the mouse Gata4 gene directs its expression ...