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Artículo
Immune signaling kinases in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Amyotrophic lateral sclerosis (ALS) is the most common neurodegenerative disorder of motor neurons in adults, with a median survival of 3–5 years after appearance of symptoms, and with no curative treatment currently ...
Artículo
Distinct responses of human peripheral blood cells to different misfolded protein oligomers
(Wiley-Blackwell, 2021)
Increasing evidence indicates that peripheral immune cells play a prominent role in neurodegeneration connected to protein misfolding, which are associated with formation of aberrant aggregates, including soluble protein ...