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Mostrando ítems 1-10 de 35
Artículo
Porous titanium substrates coated with a bilayer of bioactive glasses
(Elsevier, 2020-09)
Porous titanium substrates coated by dripping-sedimentation technique with a novel bilayer of (45S5 / 1393) bioactive glasses are proposed to overcome some limitations of the use of titanium for implants, such as the stress ...
Artículo
Synthesis and deposition of silver nanoparticles on porous titanium substrates for biomedical applications
(Elsevier, 2021-01)
Ti implants are highly biocompatible and allow orderly bone growth but, unfortunately, in the first five years after implantation, 5–10% of them fail due to poor osseointegration and to the presence of bacterial infections ...
Artículo
GPR120/FFAR4 Pharmacology: Focus on Agonists in Type 2 Diabetes Mellitus Drug Discovery
(American Chemical Society, 2021)
The G-protein coupled receptors (GPCRs) activated by free fatty acids (FFAs) have emerged as new and exciting drug targets, due to their plausible translation from pharmacology to medicines. This perspective aims to report ...
Artículo
Bi-Magnetic Core-Shell CoFe2O4@MnFe2O4 Nanoparticles for In Vivo Theranostics
(MDPI, 2020)
In this work, we report the synthesis and characterization of three magnetic nanosystems, CoFe2O4, CoFe2O4@ZnFe2O4, and CoFe2O4@MnFe2O4, which were developed as potential theranostic agents for magnetic hyperthermia and ...
Artículo
The effect of age on binocular vision normative values
(Slack, Inc., 2020)
Purpose: To establish a relationship between age and horizontal heterophoria, horizontal fusional vergence amplitudes, and vergence facility testing. Methods: The sample consisted of 112 patients with a mean age of 39.8 ± ...
Artículo
Passive targeting of high-grade gliomas via the EPR effect: a closed path for metallic nanoparticles?
(Royal Society of Chemistry, 2021-10-28)
Passive tumor targeting via the enhanced permeability and retention (EPR) effect has long been considered the most effective mechanism for the accumulation of nanoparticles inside solid tumors. However, several studies ...
Artículo
Magnetic Nanoparticles as MRI Contrast Agents
(Springer, 2020)
Iron oxide nanoparticles (IONPs) have emerged as a promising alternative to conventional contrast agents (CAs) for magnetic resonance imaging (MRI). They have been extensively investigated as CAs due to their high ...
Artículo
Exploiting Generative Design for 3D Printing of Bacterial Biofilm Resistant Composite Devices
(Wiley-Blackwell, 2021)
As the understanding of disease grows, so does the opportunity for personalization of therapies targeted to the needs of the individual. To bring about a step change in the personalization of medical devices it is shown ...
Artículo
Biofunctionalization of Porous Ti Substrates Coated with Ag Nanoparticles for Potential Antibacterial Behavior
(MDPI, 2021-04)
Ti prosthesis have shown better biological compatibility, mechanical performance, and resistance to corrosion in cases of bone replacements. Nevertheless, fully dense Ti in connection with bone-host tissues show stress-shielding ...
Artículo
Design, synthesis and in vitro biological evaluation of a novel class of anti-adenovirus agents based on 3-amino-1,2-propanediol
(Elsevier, 2021)
Nowadays there is not an effective drug for the treatment of infections caused by human adenovirus (HAdV) which supposes a clinical challenge, especially for paediatric and immunosuppressed patients. Here, we describe the ...