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Mostrando ítems 141-150 de 173
Artículo
Structurally simple redox polymersomes for doxorubicin delivery
(Elsevier, 2020-08-15)
A simple redox amphiphilic tri-block copolyurethane capable of assembling in the form of polymersome has been easily synthesized. Thus, the hydrophobic core is constituted by a central block containing multiple disulfide ...
Artículo
A comparative study of the antiangiogenic activity of hydroxytyrosyl alkyl ethers
(Elsevier, 2020)
The phenolic compound hydroxytyrosol and its derivatives are responsible for some of the health benefits of the intake of virgin olive oil, having shown antiangiogenic properties. In this study, we explored the antiangiogenic ...
Artículo
New sulfur-phosphine ligands derived from sugars: synthesis and application in palladium-catalyzed allylic alkylation and in rhodium asymmetric hydrogenation
(Arkat USA, 2008)
An efficient route to mixed phosphine / thioglycoside ligands type IV starting from glucose pentaacetate is reported. In only five steps the key epoxide 6 has been obtained in high yield and its structure determined by ...
Artículo
Nanostructured Chitosan-Based Biomaterials for Sustained and Colon-Specific Resveratrol Release
(MDPI, 2019-01)
In the present work, we demonstrate the preparation of chitosan-based composites as vehicles of the natural occurring multi-drug resveratrol (RES). Such systems are endowed with potential therapeutic effects on inflammatory ...
Artículo
Derivados del pirrol xxi. Reaccion de 2-amin0-2-desoxi-heptosas con 2,4-pentanodiona y 1-fenil-1,3-butanodiona
(1979)
Por reacción de las 2-amino-2-<lesoxi·heptosas de configuraciones D-glieero·L·glueo (la). D·glieero·D-talo (lb) y D-gfieero·D·ido (le) con 2,4-pentanodiona (11) se han obtenido los 3-acetil-2-metil-5-(pentahidroxipentil)pirroles, ...
Artículo
Development of porous silver nanoparticle/polycaprolactone/polyvinyl alcohol coatings for prophylaxis in titanium interconnected samples for dental implants
(Elsevier, 2022)
Stress shielding phenomenon, poor osseointegration, or bacterial infections of titanium dental implants are widely recognized as key problems that deeply affect their survival rate. In this work, a joint solution to solve ...
Artículo
An Efficient and Practical Method for the Enantioselective Synthesis of Tertiary Trifluoromethyl Carbinols
(Wiley Online Library, 2018-03)
An efficient sulfinamide/olefin based chiral ligand, MetSulfolefin, has been developed for the enantioselective rhodium-catalysed addition of aryl-boronic acids to trifluoromethyl ketones. This shelf-stable ligand is ...
Artículo
Carbohydrate-DNA interactions at G-quadruplexes: Folding and stability changes by attaching sugars at the 5′-End
(Wiley-Blackwell, 2013)
Quadruplex DNA structures are attracting an enormous interest in many areas of chemistry, ranging from chemical biology, supramolecular chemistry to nanoscience. We have prepared carbohydrate-DNA conjugates containing the ...
Artículo
Comparative cytotoxic activity of hydroxytyrosol and its semisynthetic lipophilic derivatives in prostate cancer cells
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
A high adherence to a Mediterranean diet has been related to numerous beneficial effects in human health, including a lower incidence and mortality of prostate cancer (PCa). Olive oil is an important source of phenolic ...
Artículo
Loading studies of the anticancer drug camptothecin into dual stimuli-sensitive nanoparticles. Stability scrutiny
(Elsevier, 2018-10-25)
In recent years, the preparation of valuable drug delivery systems (DDS) from self-assembled amphiphilic copolymers has attracted much attention since these nanomaterials provide new opportunities to solve problems such ...