Química Orgánica y Farmacéutica: Envíos recientes
Mostrando ítems 21-40 de 234
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Surface-Active Properties of Lipophilic AntioxidantsTyrosol and Hydroxytyrosol Fatty Acid Esters: A PotentialExplanation for the Nonlinear Hypothesis of the AntioxidantActivity in Oil-in-Water Emulsions
(American Chemical Society, 2001)Our group has recently observed a nonlinear tendency in antioxidant capacity of different hydroxytyrosol fatty acid esters ...
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Highly Polar Carbohydrates Stack Onto DNA Duplexes Via CH/π Interactions
(American Chemical Society, 2011)Carbohydrate-nucleic acid contacts are known to be a fundamental part of some drug-DNA recognition processes. Most of these ...
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(R)-8-Methylsulfinyloctyl isothiocyanate from Nasturtium officinale inhibits LPS-induced immunoinflammatory responses in mouse peritoneal macrophages: chemical synthesis and molecular signaling pathways involved
(Royal Society of Chemistry, 2023-07-20)The aim of this study was to develop an optimal synthetic route to obtain natural (R)-8-methylsulfinyloctyl isothiocyanate ...
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Structurally simple redox polymersomes for doxorubicin delivery
(Elsevier, 2020-08-15)A simple redox amphiphilic tri-block copolyurethane capable of assembling in the form of polymersome has been easily synthesized. ...
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Loading studies of the anticancer drug camptothecin into dual stimuli-sensitive nanoparticles. Stability scrutiny
(Elsevier, 2018-10-25)In recent years, the preparation of valuable drug delivery systems (DDS) from self-assembled amphiphilic copolymers has ...
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Preparation of water-soluble glycopolymers derived from five-membered iminosugars
(Elsevier, 2019-10)Iminosugars are carbohydrate mimetics that constitute the main group of oligosaccharide processing enzyme inhibitors. ...
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Core cross-linked nanoparticles from self-assembling polyfma-based micelles. Encapsulation of lipophilic molecules
(Elsevier, 2017-04)The present work describes the preparation of stable organic nanoparticles with potential use as “smart” drug delivery ...
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N -Isopropylsulfinylimines vs. N-tert -butylsulfinylimines in the stereoselective synthesis of sterically hindered amines: An improved synthesis of enantiopure (R)- And (S)-rimantadine and the trifluoromethylated analogues
(Royal Society of Chemistry, 2019-11-04)An improved fully stereoselective synthesis of both enantiomers of rimantadine and its trifluoromethylated analogues has ...
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Passive targeting of high-grade gliomas via the EPR effect: a closed path for metallic nanoparticles?
(Royal Society of Chemistry, 2021-10-28)Passive tumor targeting via the enhanced permeability and retention (EPR) effect has long been considered the most effective ...
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Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyran core: Switch from antagonist to agonist effect by chemical modification
(Elsevier, 2017)A library of 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyrans has been synthesized as a new family of non-peptide ...
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Comprehensive Toxicity Assessment of PEGylated Magnetic Nanoparticles for in vivo applications
(Elsevier, 2019-05-01)Magnetic nanoparticles (MNPs) represent one of the greatest promises for the development of a new generation of diagnostic ...
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Clickable iron oxide NPs based on catechol derived ligands: synthesis and characterization
(Taylor and Francis Group, 2020-03-05)Clickable magnetic nanoparticles have attracted great attention as potential nanoplatforms for biomedical applications ...
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PEGylated Terbium-Based Nanorods as Multimodal Bioimaging Contrast Agents
(American Chemical Society, 2021)Diagnostic imaging strongly relies on the use of contrast agents (CAs). In general terms, current CAs present undesirable ...
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Scaling Up Magnetic Nanobead Synthesis with Improved Stability for Biomedical Applications
(American Chemical Society, 2022)The growing interest in multifunctional nano-objects based on polymers and magnetic nanoparticles for biomedical applications ...
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Deciphering the Parameters to Produce Highly Reproducible and Scalable Iron Oxide Nanoparticles
(Royal Society of Chemistry, 2023)Nanomedicine has been long hailed as a game changer for treating several ailments, but its translation from bench to bedside ...
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Biological Evaluation of Carbohydrate-based Aprepitant Analogs for Neuroblastoma Treatment
(Elsevier, 2024)Different studies using Aprepitant, a NK1R antagonist currently used as a clinical drug for treating chemotherapy-related ...
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Synthesis and Characterization of New Carbohydrate-based Polyureas
(Tech Science Press, 2013-07)A batch of linear [m,n]-type sugar-based polyureas was synthesized by polyaddition reaction in solution from hexamethylene ...
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Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2-substituted-piperazine Derivatives as Potential Anticancer Agents-In Vitro Evaluation against Breast Cancer Cells
(MDPI, 2023)first_pagesettingsOrder Article Reprints Open AccessArticle Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2-substituted-piperazine ...
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Influence of the porosity and type of bioglass on the micro-mechanical and bioactive behavior of coated porous titanium substrates
(Elsevier, 2021-01)In this study, the best equilibrium among adherence, micro-mechanical properties and coating bioactivity of bioactive ...
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Applications and multidisciplinary perspective on 3D printing techniques: Recent developments and future trends
(Elsevier, 2023-12)n industries as diverse as automotive, aerospace, medical, energy, construction, electronics, and food, the engineering ...