• Article
  

  Expression and Functionality Study of 9 Toll-Like Receptors in 33 Drug-Naïve Non-Affective First Episode Psychosis Individuals: A 3-Month Study 

  Juncal-Ruiz, María; Riesco-Dávila, Laura; Vázquez-Bourgon, Javier; Ortiz García de la Foz, Víctor; Mayoral-van Son, Jaqueline; Ayesa-Arriola, Rosa; Setien-Suero, Esther; Leza, Juan Carlos; López-Hoyos, Marcos; Crespo Facorro, Benedicto (MDPI, 2020)

  Toll-like receptors (TLRs) are a pivotal component of the innate immune system that seem to have a role in the pathogenesis ...

• Article
  

  Cost of Relapse Management in Patients with Schizophrenia in Italy and Spain: Comparison Between Lurasidone and Quetiapine XR 

  Restelli, Umberto; García-Goñi, Manuel; Lew‑Starowicz, Michal; Mierzejewski, Pawel; Silvola, Sofia; Mayoral‑van Son, Jacqueline; Croce, David; Rocca, Paola; Crespo Facorro, Benedicto (Springer Nature, 2020)

  Background and Objective Schizophrenia is a low-prevalence mental disorder with a global age-standardized prevalence of ...

• Article
  

  Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium 

  Constantinides, Constantinos; Han, Laura K.M.; Alloza, Clara; Antonucci, Linda Antonella; Arango, Celso; Ayesa-Arriola, Rosa; Crespo Facorro, Benedicto; Walton, Esther (NATURE PUBLISHING GROUP, 2023)

  Schizophrenia (SZ) is associated with an increased risk of life-long cognitive impairments, age-related chronic disease, ...

• Article
  

  In vivo white matter microstructure in adolescents with early-onset psychosis: a multi-site mega-analysis 

  Barth, Claudia; Kelly, Sinead; Nerland, Stener; Jahanshad, Neda; Alloza, Clara; Ambrogi, Sonia; Crespo Facorro, Benedicto; Agartz, Ingrid (NATURE PUBLISHING GROUP, 2023)

  Emerging evidence suggests brain white matter alterations in adolescents with early-onset psychosis (EOP; age of onset <18 ...

• Article
  

  Polygenic risk scores enhance prediction of body mass index increase in individuals with a first episode of psychosis 

  Muntane, Gerard; Vázquez-Bourgon, Javier; Sada, Ester; Martorell, Lourdes; Papiol, Sergi; Bosch, Elena; Navarro, Arcadi; Crespo Facorro, Benedicto; Vilella, Elisabet (ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2023)

  Background. Individuals with a first episode of psychosis (FEP) show rapid weight gain during the first months of treatment, ...

• Article
  

  Suicidal thoughts and burnout among physicians during the first wave of the COVID-19 pandemic in Spain 

  Vega Sánchez, Diego de la; Irigoyen-Otiñano, María; Carballo, Juan José; Guija Villa, Julio Antonio; Giner Jiménez, Lucas (Elsevier, 2023)

  Background: The exact mechanisms through which the impact of the SARS-CoV-2 pandemic could influence the prevalence of ...

• Article
  

  Depression in the Elderly. Consensus Statement of the Spanish Psychogeriatric Association 

  Agüera-Ortiz, Luis; Claver-Martín, María Dolores; Franco Fernández, María Dolores; López-Álvarez, Jorge; Martín-Carrasco, Manuel; Ramos-García, María Isabel; Sánchez-Pérez, Manuel (Frontiers Media, 2020)

  Introduction: Present knowledge about depression in the elderly is still scarce and often controversial, despite its high ...

• Article
  

  Antipsychotic Treatment Effectiveness in First Episode of Psychosis: PAFIP 3-Year Follow-Up Randomized Clinical Trials Comparing Haloperidol, Olanzapine, Risperidone, Aripiprazole, Quetiapine, and Ziprasidone 

  Gómez-Revuelta, Marcos; Pelayo-Terán, José María; Juncal-Ruiz, María; Vázquez-Bourgon, Javier; Suárez-Pinilla, Paula; Romero-Jiménez, Rodrigo; Crespo Facorro, Benedicto (Oxford University Press, 2020)

  Background: Different effectiveness profiles among antipsychotics may be a key point to optimize treatment in patients ...

• Article
  

  miRNAs as biomarkers of autism spectrum disorder: a systematic review and meta-analysis 

  Garrido-Torres, Nathalia; Guzmán-Torres, Karem; García-Cerro, Susana; Pinilla Bermúdez, Gladys; Cruz-Baquero, Claudia; Ochoa, Hansel; Crespo Facorro, Benedicto; Ruiz Veguilla, Miguel (Springer, 23)

  Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex clinical manifestations that arise between ...

• Article
  

  Proposed recommendations for the management of depression in adults with epilepsy: an expert consensus 

  Villanueva, Vicente; Artal, Jesús; Cabeza-Álvarez, Clara-Isabel; Campos, Dulce; Castillo, Ascensión; Flórez, Gerardo; Gotor Sánchez-Luengo, Francisco; Bobes, Julio (Springer, 2023)

  Introduction: Experts agree that there is a need for protocols to guide health professionals on how to best manage ...

• Article
  

  Data of a meta-analysis on pharmacological treatment strategies for lowering prolactin in people with a psychotic disorder and hyperprolactinaemia 

  Labad, Javier; Montalvo, Itziar; González-Rodríguez, Alexandre; García-Rizo, Clemente; Crespo Facorro, Benedicto; Monreal, José Antonio; Palao, Diego (Elsevier, 2020)

  The data presented in this paper describe supplementary material to the article entitled “Pharmacological treatment ...

• Article
  

  Aripiprazole and Risperidone Present Comparable Long-Term Metabolic Profiles: Data From a Pragmatic Randomized Controlled Trial in Drug-Naïve First-Episode Psychosis 

  Vázquez-Bourgon, Javier; Ortiz García de la Foz, Víctor; Gómez-Revuelta, Marcos; Mayoral-van Son, Jaqueline; Juncal-Ruiz, María; Garrido-Torres, Nathalia; Crespo Facorro, Benedicto (Oxford University Press, 2022-05-31)

  Objective Aripiprazole and risperidone are 2 of the most used second-generation antipsychotics (SGAs) worldwide. Previous ...

• Article
  

  Clinical predictors of antipsychotic treatment resistance: Development and internal validation of a prognostic prediction model by the STRATA-G consortium 

  Smart, Sophie E.; Agbedjro, Deborah; Pardiñas, Antonio F.; Ajnakina, Olesya; Alameda, Luis; Andreassen, Ole A.; Crespo Facorro, Benedicto; MacCabe, James H. (Elsevier, 2022-10-12)

  Introduction Our aim was to, firstly, identify characteristics at first-episode of psychosis that are associated with ...

• Article
  

  Proposed recommendations for the management of depression in adults with epilepsy: an expert consensus 

  Villanueva, Vicente; Artal, Jesús; Cabeza-Álvarez, Clara-Isabel; Campos, Dulce; Castillo, Ascensión; Flórez, Gerardo; Gotor Sánchez-Luengo, Francisco; Bobes, Julio (Springer, 2023)

  Experts agree that there is a need for protocols to guide health professionals on how to best manage psychiatric ...

• Article
  

  Gene set enrichment analysis of pathophysiological pathways highlights oxidative stress in psychosis 

  Pistis, Giorgio; Vázquez-Bourgon, Javier; Fournier, Margot; Jenni, Raoul; Cleusix, Martine; Papiol, Sergi; Crespo Facorro, Benedicto; Q Do, Kim (Springer Nature, 2022-09-21)

  Polygenic risk prediction remains an important aim of genetic association studies. Currently, the predictive power of ...

• Article
  

  Structural brain alterations associated with suicidal thoughts and behaviors in young people: results from 21 international studies from the ENIGMA Suicidal Thoughts and Behaviours consortium 

  van Velzen, Laura S.; Dauvermann, Maria R.; Colic, Lejla; Villa, Luca M.; Savage, Hannah S.; Toenders, Yara J.; Crespo Facorro, Benedicto; Schmaal, Lianne (Springer Nature, 2022-09-07)

  Identifying brain alterations associated with suicidal thoughts and behaviors (STBs) in young people is critical to ...

• Article
  

  Pattern of long-term weight and metabolic changes after a first episode of psychosis Results from a 10-year prospective follow-up of the PAFIP program for early intervention in psychosis cohort 

  Vázquez-Bourgon, Javier; Gómez-Revuelta, Marcos; Mayoral-van Son, Jaqueline; Labad, Javier; Ortiz García de la Foz, Víctor; Setién Suero, Esther; Ayesa-Arriola, Rosa; Tordesillas-Gutiérrez, Diana; Juncal-Ruiz, María; Crespo Facorro, Benedicto (Cambridge University Press, 2022-08-16)

  Background People with psychosis are at higher risk of cardiovascular events, partly explained by a higher predisposition ...

• Article
  

  A Guideline and Checklist for Initiating and Managing Clozapine Treatment in Patients with Treatment-Resistant Schizophrenia 

  Correll, C. U.; Agid, Ofer; Crespo Facorro, Benedicto; de Bartolomeis, Andrea; Fagiolini, Andrea; Seppälä, Niko; Howes, Oliver D. (Springer, 2022-06-27)

  Treatment-resistant schizophrenia (TRS) will affect about one in three patients with schizophrenia. Clozapine is the only ...

• Article
  

  The psychosis metabolic risk calculator (PsyMetRiC) for young people with psychosis: International external validation and site-specific recalibration in two independent European samples 

  Perry, Benjamin I.; Vandenberghe, Frederik; Garrido Torres, Nathalia; Osimo, Emanuele F.; Piras, Marianna; Vázquez-Bourgon, Javier; Ruiz Veguilla, Miguel; Crespo Facorro, Benedicto (Elsevier, 2022-08-19)

  Background Cardiometabolic dysfunction is common in young people with psychosis. Recently, the Psychosis Metabolic Risk ...

• Article
  

  Análisis de los resultados en una encuesta de prevalencia sobre el consumo de bebidas alcohólicas en la provincia de Sevilla 

  Gili-Miner, Miguel; Giner-Ubago, J.; Lacalle Remigio, Juan Ramón; Franco Fernández, María Dolores; Perea-Milla, E.; Sariego Morillo, A.; Fernández Palacín, Ana; Millán Sáez, C. (Aran Ediciones, 1988)

  Se analizan los resultados de una encuesta sobre el consumo de bebidas alcohólicas en una muestra representativa de la ...

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