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Mostrando ítems 1-10 de 72
Artículo
Molecular and Immunological Characterization of Gluten Proteins Isolated from Oat Cultivars That Differ in Toxicity for Celiac Disease
(Public Library of Science, 2012)
A strict gluten-free diet (GFD) is the only currently available therapeutic treatment for patients with celiac disease (CD). Traditionally, treatment with a GFD has excluded wheat, barley and rye, while the presence of ...
Artículo
Diversity in oat potential immunogenicity: basis for the selection of oat varieties with no toxicity in coeliac disease
(BMJ Publishing Group, 2011)
Background and aims Coeliac disease (CD) is triggered by an abnormal reaction to gluten. Peptides resulting from partially digested gluten of wheat, barley or rye cause inflammation of the small intestinal mucosa. ...
Artículo
Alternative grains as potential raw material for gluten– free food development in the diet of celiac and gluten– sensitive patients
(Austin Publishing Group, 2014)
Celiac disease is an autoimmune disorder resulting from gluten intolerance and is based on a genetic predisposition. Gluten is a protein composite found in the cereals wheat, rye, barley and certain oat varieties. A ...
Tesis Doctoral
Artículo
Clinical Utility of Urinary Gluten Immunogenic Peptides in the Follow-up of Patients with Coeliac Disease
(Wiley-Blackwell, 2023)
Background: Gluten-free diet (GFD) is the only treatment for patients with coeliac disease (CD). and its compliance should be monitored to avoid cumulative damage. Aims: To analyse gluten exposures of coeliac patients on ...
Artículo
A new microbial gluten-degrading prolyl endopeptidase: Potential application in celiac disease to reduce gluten immunogenic peptides
(PLOS, 2019)
Gluten is a complex of proteins present in barley, wheat, rye and several varieties of oats that triggers celiac disease in genetically predisposed subjects. Gluten is notoriously difficult to digest by mammalian proteolytic ...
Artículo
Dynamics and Considerations in the Determination of the Excretion of Gluten Immunogenic Peptides in Urine: Individual Variability at Low Gluten Intake
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Background: A lifelong strict gluten-free diet is the only available treatment for celiac disease, but total exclusion of gluten is difficult to achieve. The aim of this study was to determine the range of time and the ...
Artículo
Effector specificity mutants of the transcriptional activator NahR of naphthalene degrading Pseudomonas define protein sites involved in binding of aromatic inducers
(American Society for Biochemistry and Molecular Biology Inc., 1997)
This work reports a genetic analysis of the interactions between NahR, the LysR-type regulator of the NAH operons for biodegradation of naphthalene in Pseudomonas, and its aromatic effectors. Six mutants encoding NahR ...
Capítulo de Libro
Tesis Doctoral
Nuevas estrategias para el control de la enfermedad celíaca: caracterización de los péptidos imunogénicos del gluten y validación clínica de un biomarcador para el seguimiento del paciente celíaco
(2021-03-19)
La enfermedad celiaca (EC) se define como una enteropatía inflamatoria crónica del intestino delgado causada por la ingesta de gluten en individuos genéticamente predispuestos. El término gluten hace referencia a las ...