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Browsing Artículos (Farmacia y Tecnología Farmacéutica) by Author "Aguilar de Leyva, Mercedes Ángela"
Now showing items 1-16 of 16
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Article
3D printed drug delivery systems based on natural products
Aguilar de Leyva, Mercedes Ángela; Linares Blasco, Vicente; Casas Delgado, Marta; Caraballo Rodríguez, Isidoro (Multidisciplinary Digital Publishing Institute (MDPI), 2020)In the last few years, the employment of 3D printing technologies in the manufacture of drug delivery systems has increased, ...
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Article
3D Printed Fractal-like Structures with High Percentage of Drug for Zero-Order Colonic Release
Linares Blasco, Vicente; Aguilar de Leyva, Mercedes Ángela; Casas Delgado, Marta; Caraballo Rodríguez, Isidoro (MDPI, 2022)Colonic drug delivery of drugs is an area of great interest due to the need to treat high prevalence colonic local diseases ...
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Article
3D Printing DirePowder Extrusion in the Production of Drug Delivery Systems: State of the Art and Future Perspectives
Aguilar de Leyva, Mercedes Ángela; Casas Delgado, Marta; Ferrero Rodríguez, Carmen; Linares Blasco, Vicente; Caraballo Rodríguez, Isidoro (MDPI, 2024-03-22)The production of tailored, on-demand drug delivery systems has gained attention in pharmaceutical development over the ...
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Article
ABP con plataforma virtual para los alumnos de biofarmacia y farmacocinética y farmacia galénica general
Aguilar de Leyva, Mercedes Ángela; Caraballo Rodríguez, Isidoro (Revista d’educació superior en Farmàcia, 2013)Problem based Learning (PBL) is a technique for educational innovation that has the advantage of turning the student into ...
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Article
Application of ultrasound-assisted compression and 3D-printing semi-solid extrusion techniques to the development of sustained-release drug delivery systems based on a novel biodegradable aliphatic copolyester
Ferrero Rodríguez, Carmen; Urpí, Lourdes; Aguilar de Leyva, Mercedes Ángela; Mora Castaño, Gloria; Linares Blasco, Vicente; Millán Jiménez, Mónica; Martínez de Ilarduya, Antxon; Caraballo Rodríguez, Isidoro (Elsevier, 2024)The purpose of this study was to investigate the ability of two advanced hot-processing technologies, Ultrasound-Assisted ...
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Article
Collaboration between HPMC and NaCMC in order to Reach the Polymer Critical Point in Theophylline Hydrophilic Matrices
Contreras Chávez, Lourdes Paola; Melgoza Contreras, Luz María; Aguilar de Leyva, Mercedes Ángela; Caraballo Rodríguez, Isidoro (Hindawi Publishing Corporation, 2012)Percolation theory has been applied in order to study the existence of critical points as well as the possibility to find ...
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Article
Critical points in ethylcellulose matrices: Influence of the polymer, drug and filler properties
Cifuentes, Celia; Aguilar de Leyva, Mercedes Ángela; Rajabi Siahboomi, Ali R.; Caraballo Rodríguez, Isidoro (Hrvatsko Farmaceutsko Drustvo/Croatian Pharmaceutical Society, 2013)Percolation theory has been applied to study the drug re- lease behaviour in multicomponent inert matrices con- taining ...
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Article
Design Space and Critical Points in Solid Dosage Forms
Aguilar de Leyva, Mercedes Ángela; Campiñez, María Dolores; Casas Delgado, Marta; Caraballo Rodríguez, Isidoro (Elsevier, 2017)The current regulatory environment based on the ICH guidelines encourages a systematic and science-based approach in the ...
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Article
Development and Characterization of New Functionalized Polyurethanes for Sustained and Site-specific Drug Release in the Gastrointestinal Tract
Campiñez, María Dolores; Benito Hernández, Elena María; Romero Azogil, Lucía; Aguilar de Leyva, Mercedes Ángela; García Martín, María de Gracia; Galbis Pérez, Juan Antonio; Caraballo Rodríguez, Isidoro (Elsevier, 2017)The main objective of the present paper has been the development and study of two new biodegradable polyurethanes, ...
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Article
Estudio de la utilización de fármacos antipsicóticos en una fundación pública para pacientes esquizofrénicos en Sevilla
Aguilar de Leyva, Mercedes Ángela; Caraballo Rodríguez, Isidoro; Herrera Carranza, Joaquín (Organización de Farmacéuticos Ibero-Latinoamericanos (OFIL), 2011)Objetivo: Analizar la farmacoterapia de dos grupos de pacientes esquizofrénicos de la Fundación Andaluza para la Integración ...
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Article
Estudio de la utilización de medicación concomitante al tratamiento antipsicótico en una fundación pública para pacientes esquizofrénicos en Sevilla
Aguilar de Leyva, Mercedes Ángela; Caraballo Rodríguez, Isidoro; Herrera Carranza, Joaquín (Organización de Farmacéuticos Ibero-Latinoamericanos (OFIL), 2011)Objetivo: Analizar la farmacoterapia de dos grupos de pacientes esquizofrénicos de la Fundación Andaluza para la Integración ...
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Article
Extrusion-based Technologies for 3D Printing: a Comparative Study of the Processability of Thermoplastic Polyurethane-based Formulations
Aguilar de Leyva, Mercedes Ángela; Linares Blasco, Vicente; Domínguez Robles, Juan; Casas Delgado, Marta; Caraballo Rodríguez, Isidoro (Taylor & Francis, 2023)Thermoplastic polyurethanes (TPU) offer excellent properties for a wide range of dosage forms. These polymers have been ...
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Article
Release Behaviour of Clozapine Matrix Pellets Based on Percolation Theory
Aguilar de Leyva, Mercedes Ángela; Sharkawi, Tahmer; Bataille, Bernard; Baylac, Gilles; Caraballo Rodríguez, Isidoro (Elsevier, 2011)The release behaviour of clozapine matrix pellets was studied in order to investigate if it is possible to explain it ...
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Article
Study of the Critical Points and the Role of the Pores and Viscosity in Carbamazepine Hydrophilic Matrix Tablets
Aguilar de Leyva, Mercedes Ángela; Cifuentes, Celia; Rajabi-Siahboomi, Ali R.; Caraballo Rodríguez, Isidoro (Elsevier, 2012)Percolation theory has been applied to estimate the Hypromellose (HPMC) percolation thresholds and the influence of the ...
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Article
Study of the Critical Points in Combined Matrix Tablets Containing Both Inert and Swelling Excipients
Aguilar de Leyva, Mercedes Ángela; Campiñez, Maria Dolores; Jost, Flavia; Gavira, Miguel; Caraballo Rodríguez, Isidoro (Elsevier, 2019)This work estimates for the first time critical points in combined matrices containing varying concentrations of the ...
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Article
Towards a rational basis for selection of excipients: Excipient Efficiency for controlled release
Casas Delgado, Marta; Aguilar de Leyva, Mercedes Ángela; Caraballo Rodríguez, Isidoro (Elsevier, 2015-10-15)There are many factors influencing the drug release behaviour from a pharmaceutical formulation as the particle size of ...