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Artículo
Melatonin administrated immediately before an intense exercise reverses oxidative stress, improves immunological defenses and lipid metabolism in football players
(Elsevier, 2012)
Acute sport exercise leads to a strong stimulation of muscle tissue and a change in the organism energy demands. This study was designed to investigate the effect of oral melatonin supplementation on human physiological ...
Artículo
Evidence of melatonin synthesis and release by mast cells. Possible modulatory role on inflammation
(Elsevier, 2010)
Mast cells take part of armamentarium immunologic for host defense against parasitic and bacterial infections. They are derived from bone marrow progenitors and can be activated by immunological and chemical stimuli in ...
Artículo
The role of melatonin in autoimmune and atopic diseases
(AIMS Press, 2016)
Melatonin is the main secretory product synthesized and secreted by the pineal gland during the night. Melatonin is a pleitropic molecule with a wide distribution within phylogenetically distant organisms and has a great ...
Artículo
Melatonin protects mast cells against cytotoxicity mediated by chemical stimuli PMACI: Possible clinical use
(Elsevier, 2013)
Melatonin has documented cytoprotective effects on a wide variety of immune cells. The mechanism of action on mast cells (RBL-2H3) still remains in the dark. We found that melatonin significantly attenuated phorbol ...
Artículo
Melatonin-synthesizing enzymes and melatonin receptor in rat thyroid cells
(Universidad de Murcia. Departamento de Biología Celular e Histología, 2012-11)
Melatonin is an indoleamine with a wide spectrum of biological activities other than transmitting photoperiod information, including antioxidant, oncostatic, anti-aging and immunomodulatory properties. Although melatonin ...
Artículo
Possible involvement of the inhibition of NF-kβ factor in anti_inflammatory actions that melatonin exert on mast cells
(2016-01-08)
Melatonin is a molecule endogenously produced in a wide variety of immune cells, including mast cells (RBL-2H3). It exhibits immunomodulatory, anti-inflammatory and anti-apoptotic properties. The physiologic mechanisms ...