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Mostrando ítems 1-9 de 9
Artículo
Obesity and Risk for Lymphoma: Possible Role of Leptin
(MDPI, 2022-12-08)
Obesity, which is considered a pandemic due to its high prevalence, is a risk factor for many types of cancers, including lymphoma, through a variety of mechanisms by promoting an inflammatory state. Specifically, over the ...
Tesis Doctoral
Papel de la leptina y su resistencia en el síndrome de ovario poliquístico y la diabetes gestacional
(2021-10-06)
La resistencia a la insulina y el síndrome metabólico al que se asocia es un problema sociosanitario de primer nivel. En la mujer el síndrome metabólico produce dos alteraciones fisiopatológicas propias que son el síndrome ...
Artículo
Leptin action in normal and pathological pregnancies
(2018)
Leptin is now considered an important signalling molecule of the reproductive system, as it regulates the production of gonadotrophins, the blastocyst formation and implantation, the normal placentation, as well as the ...
Artículo
Circulating myeloid-derived suppressor cells may be a useful biomarker in the follow-up of unvaccinated COVID-19 patients after hospitalization
(Frontiers Media S.A., 2023)
SARS-CoV-2 infection is the cause of the disease named COVID-19, a major public health challenge worldwide. Differences in the severity, complications and outcomes of the COVID-19 are intriguing and, patients with similar ...
Artículo
Circulating regulatory T cells from breast cancer patients in response to neoadjuvant chemotherapy
(Amer Publ Co, 2019)
Background: Immune escape of tumor cells is a new hallmark of cancer in general, and breast cancer, in particular. Previous studies have demonstrated that the immunological profile in peripheral blood may be a prognostic ...
Artículo
Decreased Expression of Sam68 Is Associated with Insulin Resistance in Granulosa Cells from PCOS Patients
(MDPI, 2022-09-09)
Background and objective: Polycystic ovary syndrome (PCOS) is a complex metabolic disorder associated with ovulatory dysfunction, hyperandrogenism, obesity, and insulin resistance, which leads to subfertility. PCOS is the ...
Artículo
Sam68 mediates leptin signaling and action in human granulosa cells: possible role in leptin resistance in PCOS
(BioScientifica, 2020)
Introduction: Polycystic ovary syndrome (PCOS) is a complex metabolic disorder associated with ovulatory dysfunction, hyperandrogenism, obesity, and insulin resistance, that leads to subfertility. Sam68 is an RNA-binding ...
Artículo
Leptin and Nutrition in Gestational Diabetes
(MPDI, 2020-07-02)
Leptin is highly expressed in the placenta, mainly by trophoblastic cells, where it has an important autocrine trophic effect. Moreover, increased leptin levels are found in the most frequent pathology of pregnancy: ...
Artículo
Role of leptin in inflammation and vice versa
(2020-08-16)
Inflammation is an essential immune response for the maintenance of tissue homeostasis. In a general sense, acute and chronic inflammation are different types of adaptive response that are called into action when other ...