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Artículo
Targeted Simplification Versus Antipseudomonal Broad-Spectrum Beta-Lactams in Patients With Bloodstream Infections Due to Enterobacteriaceae (SIMPLIFY): A Study Protocol for a Multicentre, Open-Label, Phase III Randomised, Controlled, Non-Inferiority Clinical Trial.
(2017-06-09)
Introduction Within the context of antimicrobial stewardship programmes, de-escalation of antimicrobial therapy is one of the proposed strategies for reducing the unnecessary use of broad-spectrum antibiotics (BSA). ...
Artículo
EUropean prospective cohort study on Enterobacteriaceae showing REsistance to CArbapenems (EURECA): a protocol of a European multicentre observational study
(2017-02-07)
Introduction: The rapid worldwide spread of carbapenem-resistant Enterobacteriaceae (CRE) constitutes a major challenge. The aim of the EUropean prospective cohort study on Enterobacteriaceae showing REsistance to ...
Artículo
Impact of the MIC of Piperacillin-Tazobactam on the Outcome of Patients with Bacteremia Due to Extended-Spectrum-B-Lactamase- Producing Escherichia coli
(American Society for Microbiology, 2013-07)
We investigated the impact of the piperacillin-tazobactam MIC in the outcome of 39 bloodstream infections due to extended- spectrum-B-lactamase-producing Escherichia coli. All 11 patients with urinary tract infections ...
Artículo
Long-term outcome of patients after a single interruption of antiretroviral therapy: a cohort study
(BioMed Central, 2012)
Background: To describe the long term outcome of patients who interrupted highly active antiretroviral therapy (HAART) once, identify the variables associated with earlier need to re-start HAART, and the response when ...
Artículo
Epidemiological and Clinical Complexity of Amoxicillin-Clavulanate- Resistant Escherichia coli
(American Society for Microbiology, 2013-07)
Two hundred twelve patients with colonization/infection due to amoxicillin-clavulanate (AMC)-resistant Escherichia coli were studied. OXA-1- and inhibitor-resistant TEM (IRT)-producing strains were associated with urinary ...
Tesis Doctoral
Bacteriemias por Escherichia coli productor de beta-lactamasas de espectro extendido epidemiología clínica y molecular
(2010)
Hasta hace poco las infecciones por Escherichia coli productor de BLEE eran infrecuentes, pero en los últimos años estamos asistiendo a un aumento en su frecuencia, por lo que estamos ante un fenómeno emergente no sólo en ...
Artículo
First Report of an OXA-23 Carbapenemase-Producing Acinetobacter baumannii Clinical Isolate Related to Tn2006 in Spain
(American Society for Microbiology, 2013-01)
A carbapenem-resistant Acinetobacter baumannii clinical isolate belonging to European clone II and sequence type 2 was recov-ered from a patient in the Son Espases hospital in Mallorca, Spain. Genetic analysis showed the ...
Artículo
Intestinal colonization due to Escherichia coli ST131: Risk factors and prevalence
(Biomed Central, 2018-11-15)
Background Escherichia coli sequence type 131 (ST131) is a successful clonal group that has dramatically spread during the last decades and is considered an important driver for the rapid increase of quinolone resistance ...
Artículo
Opportunities for antibiotic optimisation and outcome improvement in patients with negative blood cultures: study protocol for a cluster-randomised crossover trial, the NO-BACT study.
(2018-12-18)
Introduction Patients with negative blood cultures (BCx) represent 85%–90% of all patients with BCx taken during hospital admission. This population usually includes a heterogeneous group of patients admitted with ...
Artículo
Relationship Between the Quorum Network (Sensing/Quenching) and Clinical Features of Pneumonia and Bacteraemia Caused by A. baumannii
(Frontiers Research Foundation, 2018-12-17)
Acinetobacter baumannii (Ab) is one of the most important pathogens associated with nosocomial infections, especially pneumonia. Interest in the Quorum network, i.e., Quorum Sensing (QS)/Quorum Quenching (QQ), in this ...