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Mostrando ítems 1-10 de 24
Artículo
Psychometric properties of a revised Spanish 20-item Toronto Alexithymia Scale adaptation in multiple sclerosis patients
(Elsevier, 2013)
There have been a small number of investigations of alexithymia in multiple sclerosis (MS) using the 20-item Toronto Alexithymia Scale (TAS-20). However, the TAS-20 factor structure has not yet been evaluated in a MS ...
Artículo
Longitudinal analysis of the role of family functioning in substance use
(Springer, 2016)
Substance use during adolescence and emerging adulthood is a risk factor for subsequent substance abuse, and it may be related to emotional and behavioral problems. Research shows the importance of family relationships in ...
Artículo
Anxiolytic-like effects of Lupinus angustifolious protein hydrolysates in alzheimer model mice
(MDPI, 2021)
Alzheimer’s disease (AD), which is characterized by a devastating and progressive loss of memory, is the principal neurodegenerative disease in the elderly population worldwide. As a consequence, AD patients present ...
Artículo
Reappraising personal values in cancer: Meaning-in-life adaptation, meaningfulness, and quality of life
(John Wiley & Sons Ltd., 2023)
Objective This study explores the reappraisal of personal values among people with cancer post-diagnosis and its connections to meaningfulness, encompassing personal meaning and sense of meaning, and various dimensions ...
Artículo
Predicting improvement of quality of life and mental health over 18-months in multiple sclerosis patients
(Elsevier, 2021)
Background : Multiple sclerosis (MS) is a chronic neurodegenerative disease that can negatively affect functioning across a wide spectrum of domains. This study aims to investigate the development of mental health and ...
Artículo
Effective Knockdown of Gene Expression in Primary Microglia With siRNA and Magnetic Nanoparticles Without Cell Death or Inflammation
(Frontiers Media, 2018)
Microglia, the resident immune cells of the brain, have multiple functions in physiological and pathological conditions, including Alzheimer’s disease (AD). The use of primary microglial cell cultures has proved to be a ...
Artículo
Hypoxia compromises the mitochondrial metabolism of Alzheimer’s disease microglia via HIF1
(Springer, 2021)
Genetic Alzheimer’s disease (AD) risk factors associate with reduced defensive amyloid β plaque-associated microglia (AβAM), but the contribution of modifiable AD risk factors to microglial dysfunction is unknown. In AD ...
Artículo
Role of nitric oxide in gene expression regulation during cancer: epigenetic modifications and non-coding RNAs
(MDPI, 2021-06-10)
Nitric oxide (NO) has been identified and described as a dual mediator in cancer according to dose-, time- and compartment-dependent NO generation. The present review addresses the different epigenetic mechanisms, such ...
Artículo
Significance of Post-Traumatic Growth and Mental Health for Coping in Multiple Sclerosis Caregivers
(Multidisciplinary Digital Publishing Institute, 2023)
We investigated the influence of post-traumatic growth (PTG) and mental health (MH) on multiple sclerosis (MS) caregivers’ uses of coping strategies and identified biopsychosocial predictors of proactive or reactive coping. ...
Artículo
Beyond the Boundaries of Disease—Significant Post-traumatic Growth in Multiple Sclerosis Patients and Caregivers
(Frontiers Media, 2022)
Despite the negative repercussions of a chronic disease, multiple sclerosis (MS) might also lead to positive consequences. This longitudinal study explored post-traumatic growth in MS patients and attempted to identify ...