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Tesis Doctoral
Tesis Doctoral
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Desarrollo de sistemas derivados de quitosano para su aplicación frente a enfermedades degenerativas
(2020-09-18)
Como hipótesis de partida se destaca el hecho de que numerosas enfermedades multifactoriales que afectan de manera creciente a la sociedad, como el cáncer, y ciertas enfermedades neurodegenerativas, a pesar de su compleja ...
Artículo
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25th Anniversary of Molecules—Recent Advances in Green Chemistry
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Artículo
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Room Temperature Ionic Liquids in Asymmetric Hetero-Ene Type Reactions: Improving Organocatalyst Performance at Lower Temperatures
(MDPI, 2021-01)
Abstract: Room temperature ionic liquids (RTILs) have been widely used as (co)solvents in several catalytic processes modifying, in most of the cases, the catalyst activity and/or the selectivity for the studied reactions. ...
Tesis Doctoral
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Sulfoazúcares, sulfoglicolípidos y taurinas N-sustituidas
(2001-04)
En esta Tesis Doctoral se han preparado C-sulfoazúcares y C-sulfopolioles que contienen un grupo sulfonato (SO3M) en sustitución de un grupo hidroxilo. Se describe la síntesis de la 6-desoxi-6-C-sulfo-D-galactopiranosa ...
Artículo
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Synthesis and cancer growth inhibitory activities of 2-fatty-alkylated pyrrolidine-3,4-diol derivatives
(Arkat USA, 2014)
A series of new amphiphilic pyrrolidines containing dodecyl and oleyl apolar side chains were prepared and evaluated for their ability to inhibit the growth of pancreatic ductal adenocarcinoma cells in vitro. The new ...
Tesis Doctoral
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Glicomiméticos y Glicoligandos anfifílicos. Interacciones con enzimas, receptores y ácidos nucleicos
(2015-11-27)
En esta Tesis hemos preparado derivados de beta-ciclodextrina, metil alfa-D-glucopiranosa y alfa,alfa’-trehalosa adaptados para su aplicación al transporte vectorizado de fármacos, la transfección génica y/o en la modulación ...
Artículo
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The nodulation of Alfalfa by the acid-tolerant Rhizobium sp. Strain LPU83 does not require sulfated forms of Lipochitooligosaccharide nodulation signals
(American Society for Microbiology, 2011)
The induction of root nodules by the majority of rhizobia has a strict requirement for the secretion of symbiosis-specific lipochitooligosaccharides (nodulation factors [NFs]). The nature of the chemical substitution on ...
Artículo
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Recent developments in the synthesis of β-diketones
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Apart from being one of the most important intermediates in chemical synthesis, broadly used in the formation of C–C bonds among other processes, the β-dicarbonyl structure is present in a huge number of biologically and ...
Artículo
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Glucosylpolyphenols as Inhibitors of Aβ-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease
(American Chemical Society, 2020)
Despite the rapidly increasing number of patients suffering from type 2 diabetes, Alzheimer's disease, and diabetes-induced dementia, there are no disease-modifying therapies that are able to prevent or block disease ...