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AuthorPascual Hernández, Álvaro (3)Rodríguez Martínez, José Manuel (3)Aznar Martín, Javier (2)Palomares Folía, José Carlos (2)Torres Sánchez, María José (2)Agüero, J. (1)Alba, Verónica (1)Antony, Claude (1)Arroyos, Aurelio (1)Blasco, M. Dolores (1)... View MoreSubjectCiprofloxacin (1)Global response (1)Low-level quinolone resistance (1)Sensitization (1)Survival (1)Transcriptomic (1)... View MoreDate Issued2010 - 2017 (1)2000 - 2009 (5)1994 - 1999 (1)Funding agency
Ministerio de Sanidad y Consumo. España (7)
Junta de Andalucía (2)European Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER) (1)Instituto de Salud Carlos III (1)Has file(s)Yes (7)

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Article
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Characterization of the carbapenem-hydrolyzing oxacillinase oxa-58 in an Acinetobacter genospecies 3 clinical isolate 

Fernández-Cuenca, Felipe; Pascual Hernández, Álvaro; Marti, Sara; Sánchez Céspedes, Javier; Blasco, M. Dolores; Ruiz, Marc; Espinal, Paula; Alba, Verónica (American Society for Microbiology, 2008-08-01)
Based on imipenem resistance in an Acinetobacter genospecies 3 clinical isolate, we were able to identify, for the first time in this genomic species, a plasmid-encoded blaOXA-58 gene that was 100% homologous to the same ...
Article
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Detection of plasmid-mediated quinolone resistance genes in clinical isolates of Enterobacter spp. in Spain 

Calvo, Jorge; Cano, María Elicier; Rodríguez Martínez, José Manuel; Agüero, J.; Pascual Hernández, Álvaro; Velasco Ramírez, María del Carmen; Francia, M. V.; Martínez Martínez, Luis (American Society for Microbiology, 2009)
We have studied by PCR and DNA sequencing the presence of the qnrA, qnrB, qnrS, aac(6′)-Ib-cr, qepA, intI1, and ISCR1 genes in 200 clinical isolates of Enterobacter cloacae (n = 153) and E. aerogenes (n = 47) consecutively ...
Article
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Direct Detection of Rifampin- and Isoniazid-Resistant Mycobacterium tuberculosis in Auramine-Rhodamine-Positive Sputum Specimens by Real-Time PCR 

Ruiz Pérez, Maite; Torres Sánchez, María José; Llanos Rodríguez, Ana Cristina; Arroyos, Aurelio; Palomares Folía, José Carlos; Aznar Martín, Javier (American Society for Microbiology, 2004)
Our objective was to evaluate the feasibility of a molecular assay based on a real-time PCR technique, carried out with a LightCycler instrument (Roche Biochemicals), to identify Mycobacterium tuberculosis bacilli and to ...
Article
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A peripheral protein associated with the cis-Golgi network redistributes in the intermediate compartment upon brefeldin A treatment 

Ríos Sánchez, Rosa María; Tassin, Anne-Marie; Celati, Claude; Antony, Claude; Boissier, Marie-Christophe; Homberg, Jean-Claude; Bornens, Michel (Rockefeller University Press, 1994)
Human autoantibodies offer unique tools for the study of cellular constituents since they usually recognize highly conserved components, the most difficult to detect due to their low immunogenicity. The serum from a patient ...
Article
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Fatal levofloxacin failure in treatment of a bacteremic patient infected with Streptococcus pneumoniae with a preexisting parC mutation 

Cueto López, Marina de; Rodríguez Martínez, José Manuel; Soriano Pérez, Manuel Jesús; López Cerero, Lorena; Venero Recio, José Luis; Pascual Hernández, Álvaro (American Society for Microbiology, 2008)
The fatal outcome of levofloxacin treatment in a patient with bacteremic pneumonia caused by Streptococcus pneumoniae with a preexisting parC mutation is reported. Failure was due to the emergence of a gyrA mutation after ...
Article
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Use of real-time PCR and fluorimetry for rapid detection of rifampin and isoniazid resistance-associated mutations in Mycobacterium tuberculosis 

Torres Sánchez, María José; Criado, Antonio; Palomares Folía, José Carlos; Aznar Martín, Javier (American Society for Microbiology, 2000)
Very fast amplification of DNA in small volumes can be continuously monitored with a rapid cycler that incorporates fluorimetric detection. Primers were designed to amplify a 157-bp fragment of the rpoB gene spanning codons ...
Article
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Cellular Response to Ciprofloxacin in Low-Level Quinolone-Resistant Escherichia coli 

Machuca, Jesús; Recacha, Esther; Briales Martín, Alejandra; Díaz de Alba, Paula; Blázquez, Jesús; Pascual, Álvaro; Rodríguez Martínez, José Manuel (Frontiers Media, 2017)
Bactericidal activity of quinolones has been related to a combination of DNA fragmentation, reactive oxygen species (ROS) production and programmed cell death (PCD) systems. The underlying molecular systems responsible ...
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