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Mostrando ítems 321-330 de 333
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Epidemiology and risk factors of mycotic aneurysm in patients with infective endocarditis and the impact of its rupture in outcomes. Analysis of a national prospective cohort
(Oxford Univ Press, 2024)
Background. Several aspects of the occurrence and management of mycotic aneurysm (MA) in patients with infective endocarditis (IE) have not been studied. Objectives. To determine the incidence and factors associated with ...
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A broad molecular phylogeny of ciliates: Identification of major evolutionary trends and radiations within the phylum
(National Academy of Sciences, 1992)
The cellular architecture of ciliates is one of the most complex known within eukaryotes. Detailed systematic schemes have thus been constructed through extensive comparative morphological and ultrastructural analysis of ...
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Role of blaTEM and OmpC in the piperacillin-tazobactam resistance evolution by E. coli in patients with complicated intra-abdominal infection
(Elsevier, 2023)
Piperacillin-tazobactam resistance (P/T-R) is increasingly reported among Escherichia coli isolates. Although in vitro experiments have suggested that blaTEM gene plays a key role in the P/T-R acquisition, no clinical in ...
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Characterization of Extended-Spectrum β-Lactamase-Producing Shigella sonnei in Spain: Expanding the Geographic Distribution of Sequence Type 152/CTX-M-27 Clone
(American Society for Microbiology, 2022-07)
We describe the first occurrence in Spain of community cases of CTX-M-27-producing Shigella sonnei sequence type 152 (ST152), resistant to quinolones and azithromycin. The cases included adult males and also one pediatric ...
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Identification of a Stable Chromosomal Tandem Multicopy of bla(VIM-63), a New bla(VIM-2) Carbapenemase
(American Society for Microbiology, 2022-07)
This study characterizes a new genetic structure containing a multicopy of a bla(VIM-2) variant with an A676C substitution, bla(VIM-63). This gene was detected on the chromosome of two carbapenem-resistant clinical strains ...
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A lipopolysaccharide-free outer membrane vesicle vaccine protects against Acinetobacter baumannii infection
(Elsevier, 2020-01)
Outer membrane vesicles (OMVs) were isolated from an Acinetobacter strain deficient in lipopolysaccharide (LPS) due to a mutation in lpxD (IB010). Two immunizations with 10 µg of IB010 OMVs elicited total IgG, IgM, IgG1 ...
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Synergistic effect of SOS response and GATC methylome suppression on antibiotic stress survival in Escherichia coli
(https://journals.asm.org/doi/epdf/10.1128/aac.01392-22, 2023-03)
The suppression of the SOS response has been shown to enhance the in vitro activity of quinolones. Furthermore, Dam-dependent base methylation has an impact on susceptibility to other antimicrobials affecting DNA synthesis. ...
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RecA inactivation as a strategy to reverse the heteroresistance phenomenon in clinical isolates of Escherichia coli
(Elsevier, 2023-02)
RecA inhibition could be an important strategy to combat antimicrobial resistance because of its key role in the SOS response, DNA repair and homologous recombination contributing to bacterial survival. This study evaluated ...
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Application of BioFire FilmArray Blood Culture Identification panel for rapid identification of the causative agents of ventilator-associated pneumonia
(Elsevier, 2018-11)
Objective: To evaluate the ability of the BioFire FilmArray Blood Culture Identification (BCID) panel to rapidly detect pathogens producing late-onset ventilator-associated pneumonia (VAP), a severe infection often ...
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Immunization with lipopolysaccharide-free outer membrane complexes protects against Acinetobacter baumannii infection
(Elsevier, 2018-07-05)
Outer membrane complex (OMC) vaccines, which contain antigens from the bacterial outer membrane, have been developed for multiple Gram-negative bacteria. However, OMC vaccines demonstrate high endotoxin activity due to the ...