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Artículo
Quinolone Resistance Reversion by Targeting the SOS Response
(American Society for Microbiology, 2017)
Suppression of the SOS response has been postulated as a therapeutic strategy for potentiating antimicrobial agents. We aimed to evaluate the impact of its suppression on reversing resistance using a model of isogenic ...
Artículo
Synergistic Quinolone Sensitization by Targeting the recA SOS Response Gene and Oxidative Stress
(American Society for Microbiology, 2021-03-18)
Suppression of the recA SOS response gene and reactive oxygen species (ROS) overproduction have been shown, separately, to enhance fluoroquinolone activity and lethality. Their putative synergistic impact as a strategy to ...