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Artículo
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Efficacy of cefepime and imipenem in experimental murine pneumonia caused by porin-deficient Klebsiella pneumoniae producing CMY-2 β-lactamase
(American Society for Microbiology, 2005-08-01)
Previous studies have shown decreased in vitro activity of zwitterionic cephalosporins and carbapenems against porin-deficient Klebsiella pneumoniae expressing a plasmid-mediated AmpC-type β-lactamase (PACBL). The in vitro ...
Artículo
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Antibiotic use and outcome in patients with negative blood cultures, a new target population for antimicrobial stewardship interventions: A prospective multicentre cohort (NO-BACT)
(Elsevier, 2024)
Objectives: To evaluate the appropriateness of antimicrobial treatment and the risk factors for mortality in patients with negative blood cultures (BC), in order to evaluate whether this population would be a suitable target ...
Artículo
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Exopolysaccharide Production by Sinorhizobium fredii HH103 Is Repressed by Genistein in a NodD1-Dependent Manner
(Public Library of Science, 2016)
In the rhizobia-legume symbiotic interaction, bacterial surface polysaccharides, such as exopolysaccharide (EPS), lipopolysaccharide (LPS), K-antigen polysaccharide (KPS) or cyclic glucans (CG), appear to play crucial roles ...
Artículo
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Osmotic stress activates nif and fix genes and induces the Rhizobium tropici CIAT 899 Nod factor production via NodD2 by up-regulation of the nodA2 operon and the nodA3 gene
(Public Library of Science, 2019)
The symbiosis between rhizobia and legumes is characterized by a complex molecular dialogue in which the bacterial NodD protein plays a major role due to its capacity to activate the expression of the nodulation genes in ...
Artículo
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AQP1 and AQP4 Contribution to Cerebrospinal Fluid Homeostasis
(MDPI, 2019-02-24)
Aquaporin 1 (AQP1), expressed in epithelial cells of the choroid plexus, and aquaporin 4 (AQP4) present in ependymal cells and glia limitants have been proposed to play a significant role in cerebrospinal fluid (CSF) ...
Tesis Doctoral
Artículo
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Antimicrobial susceptibility pattern of Corynebacterium striatum
(American Society for Microbiology, 1996-11-01)
The in vitro activities of 16 antimicrobial agents against 86 strains of Corynebacterium striatum were evaluated by microdilution using cation- adjusted Mueller-Hinton broth. MICs at which 90% of strains were inhibited ...
Artículo
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Phenotypic and Genomic Comparison of Klebsiella pneumoniae Lytic Phages: vB_KpnM-VAC66 and vB_KpnM-VAC13
(MDPI, 2021-12-31)
Klebsiella pneumoniae is a human pathogen that worsens the prognosis of many immuno compromised patients. Here, we annotated and compared the genomes of two lytic phages that infect clinical strains of K. pneumoniae ...
Tesis Doctoral
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Desarrollo del uso terapeútico de Piocinas tipo R en el tratamiento de infecciones por Pseudomonas aeruginosa multirresistente
(2021-02-03)
La aparición y diseminación de cepas extensivamente-drogo-resistentes (XDR) junto con el desarrollo de biopelículas hacen que las infecciones por Pseudomonas aeruginosa supongan un auténtico desafío terapéutico. Para ...
Tesis Doctoral
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Localización, clonación y organización de los genes de la nodulación en Rhizobium trifolli
(1986)
1. Rhizobium trifolii RS1051 alberga tres megaplásmidos, de pesos moleculares aproximados de 190, 280 y 470 Mdal. El menor de ellos, pRtrRS1051a, es autotransmisible y el plásmido simbiótico, pSym, de esta cepa, pudiendo ...