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Preference for guanosine at first codon position in highly expressed Escherichia coli genes. A relationship with translational efficiency
(Oxford University Press, 1996)
The variation in base composition at the three codon sites in relation to gene expressivity, the latter esti- mated by the Codon Adaptation Index, has been studied in a sample of 1371 Escherichia coli genes. Correlation ...
Artículo
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Insertion hot spot for horizontally acquired DNA within a bidirectional small-RNA locus in Salmonella enterica
(American Society for Microbiology, 2008)
In Escherichia coli and Salmonella enterica, RyeA and RyeB RNAs are encoded on opposite DNA strands at the same locus. We present evidence indicating that the last 23 bp of the ryeB gene, corresponding to an internal portion ...
Artículo
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A role for the Saccharomyces cerevisiae Rtt109 histone acetyltransferase in R-loop homeostasis and associated genome instability
(Genetics Society of America, 2022)
The stability of the genome is occasionally challenged by the formation of DNA-RNA hybrids and R-loops, which can be influenced by the chromatin context. This is mainly due to the fact that DNA-RNA hybrids hamper the ...
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An Antifungal Exo-alpha 1,3-Glucanase (AGN13.1) from the Biocontrol Fungus Trichoderma harzianum
(American Society for Microbiology, 2001)
Trichoderma harzianum secretes α-1,3-glucanases when it is grown on polysaccharides, fungal cell walls, or autoclaved mycelium as a carbon source (simulated antagonistic conditions). We have purified and characterized one ...
Artículo
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Human CtIP Mediates Cell Cycle Control of DNA End Resection and Double Strand Break Repair
(American Society for Biochemistry and Molecular Biology, 2009)
In G0 and G1, DNA double strand breaks are repaired by nonhomologous end joining, whereas in S and G2, they are also repaired by homologous recombination. The human CtIP protein controls double strand break (DSB) resection, ...
Artículo
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Waddington's Landscapes in the Bacterial World
(Frontiers Media, 2021)
Conrad Waddington's epigenetic landscape, a visual metaphor for the development of multicellular organisms, is appropriate to depict the formation of phenotypic variants of bacterial cells. Examples of bacterial differentiation ...
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The C-terminal tail of ribosomal protein Rps15 is engaged in cytoplasmic pre-40S maturation
(Taylor & Francis, 2022)
The small ribosomal subunit protein Rps15/uS19 is involved in early nucleolar ribosome biogenesis and subsequent nuclear export of pre-40S particles to the cytoplasm. In addition, the C-terminal tail of Rps15 was suggested ...
Artículo
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Repression of IS200 transposase synthesis by RNA secondary structures
(Oxford University Press, 1999)
The IS200 transposase, a 16 kDa polypeptide encoded by the single open reading frame (ORF) of the insertion element, has been identified using an expression system based on T7 RNA polymerase. In wild-type IS200, two sets ...
Artículo
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The ubiK protein is an accessory factor necessary for bacterial Ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ
(American Society for Biochemistry and Molecular Biology Inc., 2017)
Ubiquinone (UQ), also referred to as coenzyme Q, is a widespread lipophilic molecule in both prokaryotes and eukaryotes in which it primarily acts as an electron carrier. Eleven proteins are known to participate in UQ ...
Tesis Doctoral