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The oxygenase CAO-1 of Neurospora crassa is a resveratrol cleavage enzyme.
(American Society for Microbiology, 2013)
The genome of the ascomycete Neurospora crassa encodes CAO-1 and CAO-2, two members of the carotenoid cleavage oxygenase family that target double bonds in different substrates. Previous studies demonstrated the role of ...
Tesis Doctoral
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RNA Helicases in 60S Ribosomal Subunit Biogenesis in Saccharomyces cerevisiae
(2020-11-10)
The ribosomes are the cellular organelles responsible for translating messenger RNA (mRNA) to proteins. In eukaryotic organisms, the ribosomes are composed by two subunits: the large subunit and the small subunit that come ...
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Spb4p, an essential putative RNA helicase, is required for a late step in the assembly of 60S ribosomal subunits in Saccharomyces cerevisiae
(Cold Spring Harbor Laboratory Press, 1998)
Spb4p is a putative ATP-dependent RNA helicase that is required for synthesis of 60S ribosomal subunits. Polysome analyses of strains genetically depleted of Spb4p or carrying the cold-sensitive spb4-1 mutation revealed ...
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Artículo
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Yeast as a model system to study metabolic impact of selenium compounds
(Shared Science Publishers, 2015)
Inorganic Se forms such as selenate or selenite (the two more abundant forms in nature) can be toxic in Saccharomyces cerevisiae cells, which constitute an adequate model to study such toxicity at the molecular level and ...
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Crosstalk between Virulence Loci: Regulation of Salmonella enterica Pathogenicity Island 1 (SPI-1) by Products of the std Fimbrial Operon
(Public Library of Science, 2012)
Invasion of intestinal epithelial cells is a critical step in Salmonella infection and requires the expression of genes located in Salmonella pathogenicity island 1 (SPI-1). A key factor for SPI-1 expression is DNA ...
Tesis Doctoral
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Yeast Genetic Analysis Reveals the Involvement of Chromatin Reassembly Factors in Repressing HIV-1 Basal Transcription
(Public Library of Science, 2009)
Rebound of HIV viremia after interruption of anti-retroviral therapy is due to the small population of CD4+ T cells that remain latently infected. HIV-1 transcription is the main process controlling post-integration latency. ...
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Adaptation of yeast cell membranes to ethanol
(American Society for Microbiology, 1987)
A highly ethanol-tolerant Saccharomyces wine strain is able, after growth in the presence of ethanol, to efficiently improve the ethanol tolerance of its membrane. A less-tolerant Saccharomyces laboratory strain, however, ...
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Cannabinoids induce cell death in leukaemic cells through Parthanatos and PARP-related metabolic disruptions
(Nature Publishing Group, 2024)
BACKGROUND: Several studies have described a potential anti-tumour effect of cannabinoids (CNB). CNB receptor 2 (CB2) is mostly present in hematopoietic stem cells (HSC). The present study evaluates the anti-leukaemic ...