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Artículo
Genomic responses to arsenic in the cyanobacterium Synechocystis sp. PCC 6803
(Public Library of Science, 2014)
Arsenic is a ubiquitous contaminant and a toxic metalloid which presents two main redox states in nature: arsenite [AsIII] and arsenate [AsV]. Arsenic resistance in Synechocystis sp. strain PCC 6803 is mediated by the ...
Artículo
Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth
(Company of Biologists: OAJ, 2014)
Target of rapamycin complex 1 (TORC1), which controls growth in response to nutrients, promotes ageing in multiple organisms. The fission yeast Schizosaccharomyces pombe emerges as a valuable genetic model system to study ...
Artículo
A metabolic strategy to enhance long-term survival by Phx1 through stationary phase-specific pyruvate decarboxylases in fission yeast
(Impact Journals, 2014)
In the fission yeast Schizosaccharomyces pombe, the stationary phase‐specific transcription factor Phx1 contributes to long‐term survival, stress tolerance, and meiosis. We identified Phx1‐dependent genes through transcriptome ...
Artículo
A new member of the thioredoxin reductase family from early uxygenic photosynthetic organisms
(Oxford University Press, 2017)
Thioredoxins (Trxs) are key components of the redox system that regulates the activity of a spectrum of target proteins through dithiol-disulfide exchange reactions. Trxs are reduced by members of the Trx reductase (TR) ...
Artículo
Cuf2 Is a Novel Meiosis-Specific Regulatory Factor of Meiosis Maturation
(Public Library of Science, 2012)
Background Meiosis is the specialized form of the cell cycle by which diploid cells produce the haploid gametes required for sexual reproduction. Initiation and progression through meiosis requires that the expression ...
Artículo
Global transcriptional profiles of the copper responses in the cyanobacterium synechocystis sp. PCC 6803
(Public Library of Science, 2014)
Copper is an essential element involved in fundamental processes like respiration and photosynthesis. However, it becomes toxic at high concentration, which has forced organisms to control its cellular concentration. We ...
Artículo
Altered nuclear tRNA metabolism in La-deleted Schizosaccharomyces pombe is accompanied by a nutritional stress response involving Atf1p and Pcr1p that is suppressible by Xpo-t/Los1p
(American Society for Cell Biology, 2012)
Deletion of the sla1+ gene, which encodes a homologue of the human RNA-binding protein La in Schizosaccharomyces pombe, causes irregularities in tRNA processing, with altered distribution of pre-tRNA intermediates. We show, ...
Artículo
Unprecedented pathway of reducing equivalents in a diflavin-linked disulfide oxidoreductase
(National Academy of Sciences, 2017)
Flavoproteinsparticipateinawidevarietyofphysiologicallyrelevant processes that typically involve redox reactions. Within this protein superfamily, there exists a group that is able to transfer reducing equivalents from FAD ...
Artículo
CopM is a novel copper-binding protein involved in copper resistance in Synechocystis sp. PCC 6803
(Wiley Open Access, 2015)
Copper resistance system in the cyanobacterium Synechocystis sp. PCC 6803 comprises two operons, copMRS and copBAC, which are expressed in response to copper in the media. copBAC codes for a heavy-metal efflux–resistance ...
Artículo
Metals in Cyanobacteria: Analysis of the Copper, Nickel, Cobalt and Arsenic Homeostasis Mechanisms
(MDPI AG, 2014)
Traces of metal are required for fundamental biochemical processes, such as photosynthesis and respiration. Cyanobacteria metal homeostasis acquires an important role because the photosynthetic machinery imposes a high ...