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Artículo
Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth
(Company of Biologists: OAJ, 2014)
Target of rapamycin complex 1 (TORC1), which controls growth in response to nutrients, promotes ageing in multiple organisms. The fission yeast Schizosaccharomyces pombe emerges as a valuable genetic model system to study ...
Artículo
A metabolic strategy to enhance long-term survival by Phx1 through stationary phase-specific pyruvate decarboxylases in fission yeast
(Impact Journals, 2014)
In the fission yeast Schizosaccharomyces pombe, the stationary phase‐specific transcription factor Phx1 contributes to long‐term survival, stress tolerance, and meiosis. We identified Phx1‐dependent genes through transcriptome ...
Artículo
Altered nuclear tRNA metabolism in La-deleted Schizosaccharomyces pombe is accompanied by a nutritional stress response involving Atf1p and Pcr1p that is suppressible by Xpo-t/Los1p
(American Society for Cell Biology, 2012)
Deletion of the sla1+ gene, which encodes a homologue of the human RNA-binding protein La in Schizosaccharomyces pombe, causes irregularities in tRNA processing, with altered distribution of pre-tRNA intermediates. We show, ...
Artículo
urg1: A Uracil-Regulatable Promoter System for Fission Yeast with Short Induction and Repression Times
(Public Library of Science, 2008)
Background The fission yeast Schizosaccharomyces pombe is a popular genetic model organism with powerful experimental tools. The thiamine-regulatable nmt1 promoter and derivatives, which take >15 hours for full induction, ...