• Artículo
      Icon

      BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis 

      Salas Lloret, Daniel; García Rodríguez, Néstor; Soto Hidalgo, Emily; González Vinceiro, Lourdes; Espejo Serrano, Carmen; Giebel, Lisanne; Huertas Sánchez, Pablo; González Prieto, Román (Nature Research, 2024-05-20)
      Deficiencies in the BRCA1 tumor suppressor gene are the main cause of hereditary breast and ovarian cancer. BRCA1 is ...
    • Artículo
      Icon

      dsRNAi-mediated silencing of PIAS2beta specifically kills anaplastic carcinomas by mitotic catastrophe 

      Rodrigues, Joana S.; Chenlo, Miguel; Bravo, Susana B.; Pérez Romero, Sihara; Suárez Fariña, María; Sobrino, Tomás; Sanz Pamplona, Rebeca; González Prieto, Román; Álvarez, Clara V. (Springer Nature, 2024-05-14)
      The E3 SUMO ligase PIAS2 is expressed at high levels in differentiated papillary thyroid carcinomas but at low levels in ...
    • Artículo
      IconIcon

      Quality-controlled ceramide-based GPI-anchored protein sorting into selective ER exit sites 

      Rodríguez Gallardo, Sofía; Sabido Bozo, Susana; Ikeda, Atsuko; Araki, Misako; Okazaki, Kouta; Nakano, Miyako; Aguilera Romero, María Auxiliadora; Cortés Gómez, Alejandro; López Martín, Sergio; Waga, Miho; Nakano, Akihiko; Kurokawa, Kazuo; Muñiz Guinea, Manuel; Funato, Kouichi (Elsevier, 2022)
      Glycosylphosphatidylinositol-anchored proteins (GPI-APs) exit the endoplasmic reticulum (ER) through a specialized export ...