dc.creator | Pontes Balanza, Beatriz | es |
dc.creator | Girldez, Ral | es |
dc.creator | Aguilar Ruiz, Jess S. | es |
dc.date.accessioned | 2021-04-13T08:53:49Z | |
dc.date.available | 2021-04-13T08:53:49Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Pontes Balanza, B., Girldez, R. y Aguilar Ruiz, J.S. (2015). Quality Measures for Gene Expression Biclusters. PLos ONE, 10 (3) | |
dc.identifier.issn | 1932-6203 | es |
dc.identifier.uri | https://hdl.handle.net/11441/107013 | |
dc.description.abstract | An noticeable number of biclustering approaches have been proposed proposed for the
study of gene expression data, especially for discovering functionally related gene sets
under different subsets of experimental conditions. In this context, recognizing groups of
co-expressed or co-regulated genes, that is, genes which follow a similar expression pattern,
is one of the main objectives. Due to the problem complexity, heuristic searches are
usually used instead of exhaustive algorithms. Furthermore, most of biclustering approaches
use a measure or cost function that determines the quality of biclusters. Having a
suitable quality metric for bicluster is a critical aspect, not only for guiding the search, but
also for establishing a comparison criteria among the results obtained by different biclustering
techniques. In this paper, we analyse a large number of existing approaches to quality
measures for gene expression biclusters, as well as we present a comparative study of
them based on their capability to recognize different expression patterns in biclusters. | es |
dc.description.sponsorship | Ministerio de Economía y Competitividad TIN2011-28956-C02 | es |
dc.format | application/pdf | es |
dc.format.extent | 24 | es |
dc.language.iso | eng | es |
dc.publisher | Public Library of Science | es |
dc.relation.ispartof | PLos ONE, 10 (3) | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.title | Quality Measures for Gene Expression Biclusters | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Lenguajes y Sistemas Informáticos | es |
dc.relation.projectID | TIN2011-28956-C02 | es |
dc.relation.publisherversion | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115497#:~:text=The%20idea%20behind%20MSA%20%5B28,levels%20for%20each%20experimental%20condition. | es |
dc.identifier.doi | 10.1371/journal.pone.0115497 | es |
dc.journaltitle | PLos ONE | es |
dc.publication.issue | 10 (3) | es |
dc.identifier.sisius | 20845087 | es |
dc.contributor.funder | Ministerio de Economía y Competitividad (MINECO). España | es |