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Mostrando ítems 1-10 de 38
Artículo
Accommodative and binocular disorders in preteens with computer vision syndrome: a cross-sectional study
(Wiley-Blackwell, 2021)
To assess computer vision syndrome (CVS) in a preteen population through an adult-validated CVS questionnaire and to evaluate how digital devices affect accommodative and binocular vision, we enrolled 309 preteens in this ...
Artículo
Neurotoxic assessment of Microcystin-LR, cylindrospermopsin andtheir combination on the human neuroblastoma SH-SY5Y cell line
(Elsevier, 2019-02-27)
Microcystin-LR (MC-LR) and Cylindrospermopsin (CYN) are produced by cyanobacteria. Although being considered as a hepatotoxin and a cytotoxin, respectively, different studies have revealed neurotoxic properties for both ...
Artículo
Evaluation of toxic effects induced by repeated exposure to Cylindrospermopsin in rats using a 28-day feeding study
(Elsevier, 2021-05)
Cylindrospermopsin (CYN) is a toxin with a world-wide increasing occurrence. It can induce toxic effects both in humans and the environment, and toxicity studies are needed to complete its toxicological profile. In this ...
Artículo
Effect of cold food storage techniques on the contents of Microcystins and Cylindrospermopsin in leaves of spinach (Spinacia oleracea) and lettuce (Lactuca sativa)
(Elsevier, 2022-11-06)
The presence of Cylindrospermopsin (CYN) and Microcystins (MCs) in vegetables is considered as a significant worldwide toxicological risk. Thus, this work aims to assess for the first time the impact of refrigeration (4 ...
Artículo
Oxidative and Inflammatory Imbalance in Placenta and Kidney of sFlt1-Induced Early-Onset Preeclampsia Rat Model
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Preeclampsia (PE) is a pregnancy-specific disorder characterized by the new onset of hypertension plus proteinuria and/or end-organ dysfunction. Here, we investigate the role of the nicotinamide adenine dinucleotide phosphate ...
Artículo
Assessment of the Extrusion Process and Printability of Suspension-Type Drug-Loaded AffinisolTM Filaments for 3D Printing
(MDPI, 2022)
Three-dimensional (3D) printing technology enables the design of new drug delivery systems for personalised medicine. Polymers that can be molten are needed to obtain extruded filaments for Fused Deposition Modelling (FDM), ...
Artículo
New Halonotius Species Provide Genomics-Based Insights Into Cobalamin Synthesis in Haloarchaea
(Frontiers Media, 2019)
Hypersaline aquatic and terrestrial ecosystems display a cosmopolitan distribution. These environments teem with microbes and harbor a plethora of prokaryotic lineages that evaded ecological characterization due to the ...
Artículo
Phylogenomics of Haloarchaea: The Controversy of the Genera Natrinema-Haloterrigena
(Frontiers Media, 2021)
The haloarchaeal genera Natrinema and Haloterrigena were described almost simultaneously by two different research groups and some strains studied separately were described as different species of these genera. Furthermore, ...
Artículo
Neuroprotective potential of verbascoside isolated from acanthus mollis l. Leaves through its enzymatic inhibition and free radical scavenging ability
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)
The phenomenon of today’s ageing population has increased interest in the search for new active substances that delay the onset and development of neurodegenerative diseases. In this respect, the search for natural compounds, ...
Artículo
Enantioselective synthesis of 4-amino-3,4-dihydrocoumarins and their non-cyclic hydroxyester precursors: Biological evaluation for the treatment of glioblastoma multiforme
(Elsevier, 2022)
The stereoselective addition of ethyl acetate enolate to the C═N bond of N-tert-butylsulfinylimines has been investigated in depth. A significant effect of the LHMDS amount and the N-sulfinylimine nature on the stereoselectivity ...