Browsing Investigación by Funding agency 

Browsing Investigación by Funding agency "Wellcome Trust. UK"

Now showing items 1-3 of 3

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      Characterizing Replisome Disassembly in Human Cells 

      Jones, Rebecca M.; Herrero Ruiz, Joaquín; caramuzza, Shaun; Nath, Sarmi; Liu, Chaoyu; Henklewska, Marta; Natsume, Toyoaki; Bristow, Robert G.; Romero Portillo, Francisco; Kanemaki, Masato T.; Gambus, Agnieszka (Elsevier, 2024)
      To ensure timely duplication of the entire eukaryotic genome, thousands of replication machineries (replisomes) act on ...
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      Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen 

      Pontel, Lucas B.; Valle Rosado, Iván; Burgos Barragán, Guillermo; Garaycoechea, Juan I.; Yu, Rui; Arends, Mark J.; Patel, Ketan J. (Cell Press, 2015)
      Endogenous formaldehyde is produced by numerous biochemical pathways fundamental to life, and it can crosslink both DNA ...
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      Xpf suppresses the mutagenic consequences of phagocytosis in Dictyostelium 

      Pontel, Lucas B.; Langenick, Judith; Valle Rosado, Iván; Zhang, Xiao-Yin; Traynor, David; Kay, Robert R.; Patel, Ketan J. (The Company of Biologists, 2016)
      As time passes, mutations accumulate in the genomes of all living organisms. These changes promote genetic diversity, but ...