dc.creator | González-Navarro, Beatríz | es |
dc.creator | Segura Egea, Juan José | es |
dc.creator | Estrugo-Devesa, Albert | es |
dc.creator | Pintó-Sala, Xavier | es |
dc.creator | Jane-Salas, Enric | es |
dc.creator | Jiménez-Sánchez, María del Carmen | es |
dc.creator | Cabanillas Balsera, Daniel | es |
dc.creator | López López, José | es |
dc.date.accessioned | 2020-12-16T18:43:35Z | |
dc.date.available | 2020-12-16T18:43:35Z | |
dc.date.issued | 2020-10-04 | |
dc.identifier.citation | González-Navarro, B., Segura Egea, J.J., Estrugo-Devesa, A., Pintó-Sala, X., Jane-Salas, ., Jiménez-Sánchez, M.d.C.,...,López López, J. (2020). Relationship between Apical Periodontitis and Metabolic Syndrome and Cardiovascular Events: A Cross-Sectional Study. Journal of Clinical Medicine, 9 (10), 1-13. https://doi.org/10.3390/jcm9103205. | |
dc.identifier.issn | 2077-0383 | es |
dc.identifier.uri | https://hdl.handle.net/11441/103330 | |
dc.description.abstract | Both apical periodontitis (AP) and metabolic syndrome (MetS) are associated with
atherosclerotic cardiovascular disease (ACVD), the main cause of cardiovascular events. The aim
of this study was to investigate the prevalence of AP and the oral inflammatory burden in control
subjects and patients suffering cardiovascular events, analyzing the possible association between AP
and the oral inflammatory burden with MetS. Materials and Methods: Using a cross-sectional design,
83 patients suffering a cardiovascular event were recruited in the study group (SG), and 48 patients
without cardiovascular events were included in the control group (CG). Periapical index (PAI) was
used to diagnose AP, and total dental index (TDI) was used to assess the total oral inflammatory
burden. Diagnosis of MetS was made by meeting three or more American Heart Association Scientific
Statement components. Results: In the multivariate logistic regression analysis, the number of teeth
with AP (OR = 2.3; 95% C.I. = 1.3–4.3; p = 0.006) and TDI scores (OR = 1.5; 95% C.I. = 1.2–1.9;
p = 0.001), significantly correlated with cardiovascular events. MetS was strongly associated (OR = 18.0;
95% C.I. = 6.5–49.7; p = 0000) with cardiovascular events. Higher TDI scores were significantly
associated with MetS (OR = 1.3; 95% C.I. = 1.1–1.6; p = 0.003. Neither the number of root-filled
teeth (RFT) (OR = 0.9; 95% C.I. = 0.6–1.3; p = 0.61) nor the number of teeth with apical periodontitis
(OR = 1.1; 95% C.I. = 0.8–1.7; p = 0.49) were associated with MetS. Conclusions: Apical periodontitis
is significantly associated with cardiovascular events. Total oral inflammatory burden assessed by
TDI, but not AP alone, is associated with MetS. | es |
dc.format | application/pdf | es |
dc.format.extent | 13 | es |
dc.language.iso | eng | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | Journal of Clinical Medicine, 9 (10), 1-13. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Apical periodontitis | es |
dc.subject | Cardiovascular disease | es |
dc.subject | Cardiovascular events | es |
dc.subject | Endodontic infection | es |
dc.subject | Metabolic syndrome | es |
dc.subject | Periapical index | es |
dc.subject | Total dental index | es |
dc.title | Relationship between Apical Periodontitis and Metabolic Syndrome and Cardiovascular Events: A Cross-Sectional Study | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Estomatología | es |
dc.relation.publisherversion | https://doi.org/10.3390/jcm9103205 | es |
dc.identifier.doi | 10.3390/jcm9103205 | es |
dc.journaltitle | Journal of Clinical Medicine | es |
dc.publication.volumen | 9 | es |
dc.publication.issue | 10 | es |
dc.publication.initialPage | 1 | es |
dc.publication.endPage | 13 | es |