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dc.creatorCabanillas Balsera, Danieles
dc.creatorSegura Egea, Juan Josées
dc.creatorBermudo Fuenmayor, Maríaes
dc.creatorMartín González, Jeniferes
dc.creatorJiménez Sánchez, María del Carmenes
dc.creatorAreal Quecuty, Victoriaes
dc.creatorSánchez Domínguez, Benitoes
dc.creatorMontero Miralles, Palomaes
dc.creatorVelasco Ortega, Eugenioes
dc.date.accessioned2020-12-15T12:32:37Z
dc.date.available2020-12-15T12:32:37Z
dc.date.issued2020
dc.identifier.citationCabanillas Balsera, D., Segura Egea, J.J., Bermudo Fuenmayor, M., Martín González, J., Jiménez Sánchez, M.d.C., Areal Quecuty, V.,...,Velasco Ortega, E. (2020). Smoking and Radiolucent Periapical Lesions in Root Filled Teeth: Systematic Review and Meta-Analysis. Journal of Clinical Medicine, 9 (11), 1-14.
dc.identifier.issn2077-0383es
dc.identifier.urihttps://hdl.handle.net/11441/103244
dc.description.abstractAim: This systematic review and meta-analysis aimed to investigate the association between smoking habits and the prevalence of radiolucent periapical lesions (RPLs) in root-filled teeth (RFT). Methods: The Population, Intervention, Comparison, and Outcome (PICO) question was: in adult patients who have RFT, does the absence or presence of a smoking habit affect the prevalence of RPLs associated with RFT? Systematic MEDLINE/PubMed, Wiley Online Database, Web of Science, Scopus, and PRISMA protocol were used to evaluate and present the results. Studies comparing smokers with control non-smoker subjects, including RFT, and providing data on the prevalence of RFT with RPLs, were included. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system was used for certainty in the evidence. The risk of bias was assessed according to Cochrane Collaboration common scheme for bias and ROBINS-I tool. Cumulative meta-analysis was performed with a random effects model. PROSPERO registration code: CRD42020165279. Results: Four studies reported data on inclusion criteria, representing data from 9257 root-filled teeth—4465 from non-smokers and 4792 from smoker patients. The meta-analysis provided an odds ratio indicating a significant association between smoking and higher prevalence of root filled teeth with radiolucent periapical lesions (OR = 1.16; 95% CI = 1.07–1.26; p = 0.0004). The certainty of the literature assessment was moderate per GRADE. The ROBINS-I tool classified three studies as low risk of bias, and the fourth as moderate risk of bias. Conclusions: Moderate, quality scientific evidence indicates a weak but significant relationship between smoking and the prevalence of RPLs in RFT. Smoking can be considered a negative prognostic factor for the outcome of root canal treatment. Endodontic providers should be aware of the relationship between smoking and persistent apical periodontitis, assessed as RPLs, in RFT.es
dc.formatapplication/pdfes
dc.format.extent14 p.es
dc.language.isoenges
dc.publisherMDPIes
dc.relation.ispartofJournal of Clinical Medicine, 9 (11), 1-14.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectendodontic medicinees
dc.subjectpersistent apical periodontitises
dc.subjectradiolucent periapical lesiones
dc.subjectroot canal treatment outcomees
dc.subjectoot-filled teethes
dc.subjectsmoking habitses
dc.titleSmoking and Radiolucent Periapical Lesions in Root Filled Teeth: Systematic Review and Meta-Analysises
dc.typeinfo:eu-repo/semantics/articlees
dcterms.identifierhttps://ror.org/03yxnpp24
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Estomatologíaes
dc.relation.publisherversionhttp://dx.doi.org/10.3390/jcm9113506es
dc.identifier.doi10.3390/jcm9113506es
dc.journaltitleJournal of Clinical Medicinees
dc.publication.volumen9es
dc.publication.issue11es
dc.publication.initialPage1es
dc.publication.endPage14es

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