Perfectly Monodisperse Microbubbling by Capillary Flow Focusing

Abstract

Here we report a simple microfluidics phenomenon which allows the efficient mass production of

micron size gas bubbles with a perfectly monodisperse and controllable diameter. It resorts on a self- excited breakup phenomenon (which locks at a certain frequency) of a short gas microligament coflowing

in a focused liquid stream. In this work, we describe the physics of the phenomenon and obtain closed expressions for the bubble diameter as a function of the liquid and gas properties, geometry, and flow parameters, from a large set of experimental results.