Browsing by Author "Pozo Pérez, David"
Now showing items 1-13 of 13
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Article
Adipose-derived mesenchymal stem cells (AdMSC) for the treatment of secondary-progressive multiple sclerosis: A triple blinded, placebo controlled, randomized phase I/II safety and feasibility study
(Public Library of Science, 2018)Background Currently available treatments for secondary progressive multiple sclerosis(SPMS) have limited efficacy ...
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PhD Thesis
Alpha-synuclein and immune system crosstalk in parkinson's disease; therapeutic approaches of its modulation by molecular chaperones
(2017-05-22)This Doctoral Thesis is focused on the interplay between the immune system and the Parkinson’s related protein alpha-Synuclein. ...
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Article
Chaperoned amyloid proteins for immune manipulation: a-Synuclein/Hsp70 shifts immunity toward a modulatory phenotype
(Wiley Open Access, 2014)α-Synuclein (αSyn) is a 140-residue amyloid-forming protein whose aggregation is linked to Parkinson's disease (PD). It ...
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Article
Distinct responses of human peripheral blood cells to different misfolded protein oligomers
(Wiley-Blackwell, 2021)Increasing evidence indicates that peripheral immune cells play a prominent role in neurodegeneration connected to protein ...
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PhD Thesis
Esclerosis lateral amiotrófica: investigaciones en el modelo sod1g93a y correlaciones de interés clínico
(2016-06-03)La esclerosis lateral amiotrófica (ELA) es una enfermedad neurodegenerativa, incurable y de carácter fatal en un plazo de ...
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Article
Histomorphogenesis and immunohistochemical study of the bovine pineal gland (Bos taurus) during prenatal development (160 days of gestation to birth)
(Universidad de Murcia. Departamento de Biología Celular e Histología, 2006-10-01)The ontogenesis of the pineal gland of 20 bovine embryos (Bos taurus) has been analysed from 160 days of gestation to birth ...
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PhD Thesis
Nanotechnology approaches for improvoved vasoactive intestinal peptide based-drug delivery systems
(2014-01-08)The specific purpose of this project is to study the feasibility as a proof of concept of different nanotechnology approaches ...
- PhD Thesis
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Article
The metabesity factor HMG20A potentiates astrocyte survival and reactive astrogliosis preserving neuronal integrity
(IVYSPRING INT PUBL, 2021)Rationale: We recently demonstrated that the ‘Metabesity’ factor HMG20A regulates islet beta-cell functional maturity ...
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Article
Titanium Surface Characteristics Induce the Specific Reprogramming of Toll-like Receptor Signaling in Macrophages
(MDPI, 2022)Most of the research on titanium-based dental implants (Ti-discs) is focused on how they are able to stimulate the formation ...
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Article
Vasoactive intestinal peptide induces regulatory dendritic cells with therapeutic effects on autoimmune disorders
(National Academy of Sciences, 2005)The induction of antigen-specific tolerance is critical for the prevention of autoimmunity and maintenance of immune ...