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Listar por autor "Vicente Munuera, Pablo"
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Artículo
A quantitative principle to understand 3D cellular connectivity in epithelial tubes
Gómez Gálvez, Pedro; Vicente Munuera, Pablo; Anbari, Samira; Tagua Jáñez, Antonio; Gordillo Vázquez, Carmen María; Palacios, Ana M.; Velasco, Antonio; Capitán Agudo, Carlos; Grima Ruiz, Clara Isabel; Robles Arias, Rafael; Márquez Pérez, Alberto; Buceta, Javier; Escudero Cuadrado, Luis María; Annese, Valentina (Cell Systems, 2022)Apico-basal cell intercalations (scutoids) optimize packing and energy expenditure in curved epithelia. Further consequences ...
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Artículo
Author Correction: Scutoids are a geometrical solution to three-dimensional packing of epithelia
Gómez Gálvez, Pedro; Vicente Munuera, Pablo; Tagua Jáñez, Antonio Jesús; Forja, Cristina; Castro Rodríguez, Ana María; Grima Ruiz, Clara Isabel; Bermúdez Gallardo, Marina; Márquez Pérez, Alberto; Escudero Cuadrado, Luis María (Nature Research, 2018) -
Artículo
CartoCell, a high-content pipeline for 3D image analysis, unveils cell morphology patterns in epithelia
Andrés San Román, Jesús Ángel; Gordillo Vázquez, Carmen María; Franco Barranco, Daniel; Morato Concejero, Laura; Huertas Fernández-Espartero, Cecilia; Baonza, Gabriel; Tagua Jáñez, Antonio Jesús; Vicente Munuera, Pablo; Palacios Barea, Ana María; Gavilán Dorronzoro, María de la Paz; Martín Belmonte, Fernando; Annese, Valentina; Gómez Gálvez, Pedro; Arganda Carreras, Ignacio; Escudero Cuadrado, Luis María (Elsevier, 2023)Decades of research have not yet fully explained the mechanisms of epithelial self-organization and 3D packing. Single-cell ...
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Artículo
EpiGraph: an open-source platform to quantify epithelial organization
Vicente Munuera, Pablo; Gómez Gálvez, Pedro; Tetley, Robert J.; Forja Barbosa, Cristina; Tagua Jáñez, Antonio Jesús; Letrán, Marta; Tozluoglu, Melda; Mao, Yanlan; Escudero Cuadrado, Luis María (Oxford University Press, 2020)Here we present EpiGraph, an image analysis tool that quantifies epithelial organization. Our method combines computational ...
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Artículo
Evolutionary 3D Image Segmentation of Curve Epithelial Tissues of Drosophila melanogaster
Capitán Agudo, Carlos; Pontes Balanza, Beatriz; Gómez Gálvez, Pedro; Vicente Munuera, Pablo (MDPI, 2021)Analysing biological images coming from the microscope is challenging; not only is it complex to acquire the images, but ...
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Artículo
Non-productive angiogenesis disassembles Aß plaque-associated blood vessels
Álvarez Vergara, Maria I.; Rosales Nieves, Alicia E.; March Díaz, Rosana Rocío; Rodríguez Perinan, Guiomar; Lara Ureña, Nieves; Ortega de San Luis, Clara; Sánchez García, Manuel A.; Martín Bornez, Miguel; Gómez Gálvez, Pedro; Vicente Munuera, Pablo; Fernández Gómez, Beatriz; Marchena, Miguel Ángel (Springer Nature, 2021)The human Alzheimer’s disease (AD) brain accumulates angiogenic markers but paradoxically, the cerebral microvasculature ...
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Artículo
Scutoids are a geometrical solution to three-dimensional packing of epithelia
Gómez Gálvez, Pedro; Vicente Munuera, Pablo; Tagua Jáñez, Antonio; Forja Barbosa, Cristina; Castro Rodríguez, Ana María; Letrán, Marta; Grima Ruiz, Clara Isabel; Bermúdez Gallardo, Marina; Serrano Pérez-Higueras, Óscar; Márquez Pérez, Alberto; Escudero Cuadrado, Luis María (Nature Publishing Group, 2018)As animals develop, tissue bending contributes to shape the organs into complex three-dimensional structures. However, the ...
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Artículo
The complex three-dimensional organization of epithelial tissues
Gómez Gálvez, Pedro; Vicente Munuera, Pablo; Anbari, Samira; Buceta, Javier; Escudero Cuadrado, Luis María (The Company of Biologists Ltd., 2021)Understanding the cellular organization of tissues is key to developmental biology. In order to deal with this complex ...
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Artículo
The topology of vitronectin: A complementary feature for neuroblastoma risk classification based on computer-aided detection
Vicente Munuera, Pablo; Burgos Panadero, Rebeca; Noguera, Inmaculada; Navarro, Samuel; Noguera, Rosa; Escudero Cuadrado, Luis María (Wiley, 2020)Tumors are complex networks of constantly interacting elements: tumor cells, stromal cells, immune and stem cells, ...
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Tesis Doctoral
Topological analysis of the tumour microenvironment to study Neuroblastoma
Vicente Munuera, Pablo (2020-09-03)Solid tumours and their tumour microenvironment (TME) can be considered as complex networks whose elements are in constant ...