- idUS
- Listar por autor
Listar por autor "Velázquez Cruz, Alejandro"
Mostrando ítems 1-11 de 11
-
Artículo
Exploring protein phosphorylation by combining computational approaches and biochemical methods
Pérez Mejías, Gonzalo; Velázquez Cruz, Alejandro; Guerra Castellano, Alejandra; Baños Jaime, Blanca; Díaz Quintana, Antonio Jesús; González Arzola, Katiuska; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Elsevier, 2020)Post-translational modifications of proteins expand their functional diversity, regulating the response of cells to a ...
-
Artículo
Hu Antigen R (HuR) Protein Structure, Function and Regulation in Hepatobiliary Tumors
Lachiondo Ortega, Sofía; Cardoso Delgado, Teresa; Baños Jaime, Blanca; Velázquez Cruz, Alejandro; Díaz Moreno, Irene; Martínez Chantar, María Luz (MDPI, 2022)Hepatobiliary tumors are a group of primary malignancies encompassing the liver, the intra- and extra-hepatic biliary ...
-
Artículo
Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome c
Rivero Rodríguez, Francisco; Díaz Quintana, Antonio Jesús; Velázquez Cruz, Alejandro; González Arzola, Katiuska; Gavilán Dorronzoro, María de la Paz; Velázquez Campoy, Adrián; Ríos Sánchez, Rosa María; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Elsevier, 2021)Repair of injured DNA relies on nucleosome dismantling by histone chaperones and de-phosphorylation events carried out by ...
-
Tesis Doctoral
Mechanistic insights into the post-translational regulation of RNA-binding proteins in cell life and disease
Velázquez Cruz, Alejandro (2024-02-01)Cell signaling networks modulate gene expression in response to internal and external stimuli. Rapid cellular adaptation ...
-
Artículo
Nuclear cytochrome c – a mitochondrial visitor regulating damaged chromatin dynamics
Díaz Moreno, Irene; Velázquez Cruz, Alejandro; Curran French, Seamus; Díaz Quintana, Antonio Jesús; Rosa Acosta, Miguel Ángel de la (Wiley-Blackwell, 2018)Over the past decade, evidence has emerged suggesting a broader role for cytochrome c (Cyt c) in programmed cell death. ...
-
Artículo
Nucleus-translocated mitochondrial cytochrome c liberates nucleophosmin-sequestered ARF tumor suppressor by changing nucleolar liquid-liquid phase separation.
González Arzola, Katiuska; Díaz Quintana, Antonio Jesús; Bernardo García, Noelia; Martínez Fábregas, Jonathan; Rivero Rodríguez, Francisco; Casado Combreras, Miguel Ángel; Elena-Real, Carlos A.; Velázquez Cruz, Alejandro; Gil Caballero, Sergio; Velázquez Campoy, Adrián; Szulc, Elzbieta; Gavilán Dorronzoro, María de la Paz; Ayala, Isabel; Arranz, Rocío; Ríos, Rosa M.; Salvatella, Xavier; Valpuesta, José María; Hermoso, Juan A.; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Nature Research, 2022-10-11)The regular functioning of the nucleolus and nucleus-mitochondria crosstalk are considered unrelated processes, yet ...
-
Artículo
Post-translational Control of RNA-Binding Proteins and Disease-Related Dysregulation
Velázquez Cruz, Alejandro; Baños Jaime, Blanca; Díaz Quintana, Antonio Jesús; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Frontiers Media S.A., 2021)Cell signaling mechanisms modulate gene expression in response to internal and external stimuli. Cellular adaptation ...
-
Artículo
Regulation of TIA-1 Condensates: Zn2+ and RGG Motifs Promote Nucleic Acid Driven LLPS and Inhibit Irreversible Aggregation
West, Danella L.; Loughlin, Fionna E.; Rivero Rodríguez, Francisco; Vankadari, Naveen; Velázquez Cruz, Alejandro; Corrales Guerrero, Laura; Díaz Moreno, Irene; Wilce, Jacqueline A. (Frontiers Media S.A., 2022)Stress granules are non-membrane bound RNA-protein granules essential for survival during acute cellular stress. TIA-1 is ...
-
Artículo
RNA Binding Protein Regulation and Cross-Talk in the Control of AU-rich mRNA Fate
García Mauriño, Sofía M.; Rivero Rodríguez, Francisco; Velázquez Cruz, Alejandro; Hernández Vellisca, Marian; Díaz Quintana, Antonio Jesús; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Frontiers Media, 2017)mRNA metabolism is tightly orchestrated by highly-regulated RNA Binding Proteins (RBPs) that determine mRNA fate, thereby ...
-
Artículo
SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
Lachiondo Ortega, Sofia; Rejano Gordillo, Claudia M.; Simon, Jorge; Lopitz Otsoa, Fernando; C. Delgado, Teresa; Mazan Mamczarz, Krystyna; Goikoetxea Usandizaga, Naroa; Velázquez Cruz, Alejandro; Díaz Quintana, Antonio Jesús; Díaz Moreno, Irene; Martínez-Chantar, María Luz (Elsevier, 2024-03-26)The posttranslational modification of proteins critically influences many biological processes and is a key mechanism that ...
-
Artículo
The Histone Chaperones SET/TAF-1β and NPM1 Exhibit Conserved Functionality in Nucleosome Remodeling and Histone Eviction in a Cytochrome c-Dependent Manner
Buzón, Pedro; Velázquez Cruz, Alejandro; Corrales Guerrero, Laura; Díaz Quintana, Antonio Jesús; Díaz Moreno, Irene; Roos, Wouter H. (Wiley-Blackwell, 2023)Chromatin homeostasis mediates essential processes in eukaryotes, where histone chaperones have emerged as major regulatory ...